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Acmella oleracea
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
Creates a remarkable electric tingling and numbing sensation; used worldwide for toothache and as an immune stimulant comparable to echinacea.
Creates a remarkable electric tingling and numbing sensation; used worldwide for toothache and as an immune stimulant comparable to echinacea. Key active compounds include Spilanthol, N-alkylamides, Polyacetylenes.
Spilanthol, along with N-alkylamides and Polyacetylenes, are the primary bioactive compounds in Spilanthes Toothache. These compounds modulates NF-κB and COX-2 inflammatory pathways, modulates immune cell activity and cytokine production, acts on pain pathways via anti-inflammatory and neuroactive effects.
Local analgesic for dental pain
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Immune modulator
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Anti-inflammatory
Toothache pain relief
Based on traditional use; clinical evidence limited
Immune stimulation in Amazonian medicine
Based on traditional use; clinical evidence limited
Saliva stimulation
Based on traditional use; clinical evidence limited
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