This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before using herbs, especially if you are pregnant, nursing, taking medications, or have a medical condition.
How does Stachys lavandulifolia work as an anti-inflammatory?
Stachys lavandulifolia exerts anti-inflammatory effects primarily through its iridoid glycosides and flavonoid compounds. These bioactive constituents appear to inhibit pro-inflammatory mediators and modulate inflammatory pathways in the body. The essential oils contribute additional anti-inflammatory and wound-healing activity. Research on precise molecular mechanisms remains limited (Evidence Level C), but traditional use and preliminary phytochemical analysis support these anti-inflammatory properties. The herb's nervine effects may also be attributed to its alkaloid content affecting the central nervous system.
Does Stachys lavandulifolia interact with any medications?
Stachys lavandulifolia may interact with central nervous system depressants due to its mild sedative properties. Combining this herb with benzodiazepines, barbiturates, or other sedatives could potentiate drowsiness and sedation. Additionally, caution is advised when taking this herb alongside anticoagulants or antiplatelet medications, as some flavonoids may affect blood clotting. Always consult a qualified healthcare provider before combining Stachys lavandulifolia with prescription medications. No formal drug interaction studies exist (Evidence Level D), so a precautionary approach is recommended.
What is the recommended dosage for Stachys lavandulifolia tea?
The traditional adult dosage for Stachys lavandulifolia is 3–5 grams of dried herb prepared as a tea, taken up to three times daily. To prepare, steep the herb in hot water for 10–15 minutes before straining. This dosing is based on Persian traditional medicine practices rather than standardized clinical trials (Evidence Level C). Dosage should be individualized based on the specific condition being treated. Always start with lower doses to assess tolerance, and consult a qualified medical herbalist for personalized recommendations.
Is Stachys lavandulifolia safe to take during pregnancy?
Stachys lavandulifolia is considered unsafe during pregnancy and should be avoided. Traditional use and pharmacological evidence suggest this herb may stimulate uterine contractions or affect fetal development, particularly at higher doses. The presence of alkaloids and essential oils raises additional safety concerns during gestation. Breastfeeding women should also avoid this herb due to insufficient safety data. If you are pregnant, nursing, or planning pregnancy, consult your healthcare provider before using any herbal preparations. This contraindication is based on traditional knowledge and pharmacological reasoning (Evidence Level D).
What is Stachys lavandulifolia used for in traditional medicine?
Stachys lavandulifolia has been used in Persian traditional medicine for centuries as a digestive aid, nervine, and anti-inflammatory agent. Common applications include treating digestive disorders such as bloating and indigestion, calming nervous tension and anxiety, reducing inflammation, promoting wound healing, and alleviating headaches. The herb's aromatic properties make it particularly valued for digestive and nervine support. While these uses are well-documented in ethnobotanical literature (Evidence Level C), modern clinical research validating these traditional applications remains limited.
What are the side effects of Stachys lavandulifolia?
Stachys lavandulifolia is generally well-tolerated at recommended doses, but some individuals may experience mild side effects. The most commonly reported effects include mild sedation or drowsiness, particularly when taken in higher doses or combined with other sedating substances. Some users report digestive upset, including nausea or stomach discomfort. Allergic reactions are possible in sensitive individuals, especially those with known allergies to plants in the Lamiaceae (mint) family. Discontinue use if adverse reactions occur. These effects are based on traditional use reports (Evidence Level D).
PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Stachys lavandulifolia, commonly known as Mountain Tea, is a perennial flowering plant of the Lamiaceae family used in traditional medicine for its anxiolytic, analgesic, and anti-inflammatory properties [PMID:38189318, PMID:40899416].
Background
Stachys lavandulifolia Vahl. is an herbaceous plant native to Iran, Turkey, Armenia, Azerbaijan, Iraq, and Turkmenistan [PMID:38189318, PMID:40899416]. In traditional Iranian medicine, it is considered equivalent to Marmazad [PMID:26734474].
Traditional uses
It is traditionally used as a mild sedative tea to reduce anxiety, for the treatment of gastrointestinal and respiratory disorders, and for painful conditions [PMID:29844776, PMID:23074920, PMID:29741912].
Active compounds
Chemical constituents include terpenoids, iridoids, flavonoids (such as apigenin, kumatakenin, and penduletin), and phenylethanoids [PMID:38189318, PMID:29844776]. Essential oil components include alpha-pinene, (E)-caryophyllene, germacrene D, delta-cadinene, alpha-thujone, and myrcene [PMID:40899416, PMID:23593591]. Other identified compounds include betulinic acid, oleanolic acid, rosmarinic acid, and ursolic acid [PMID:20738162].
Mechanism of action
The plant may act via the GABAergic and opioidergic systems to produce anticonvulsant and antispasmodic effects [PMID:36589024, PMID:24250359]. In the context of Polycystic Ovary Syndrome (PCOS), it is suggested to influence steroid hormone production, glucose homeostasis, and insulin resistance, targeting genes such as CYP19A1 and the human androgen receptor [PMID:40993927]. It may also decrease progesterone concentrations [PMID:27418911].
Clinical evidence
Evidence BOccupational Stress in EMTs
A clinical trial using 2g of tea daily for 2 months investigated its effect on occupational stress [PMID:37061348]
Evidence BPrimary Dysmenorrhea
A randomized, double-blind, crossover, placebo-controlled pilot study evaluated the efficacy of standardized capsules in reducing pain [PMID:29741912]
Evidence AVaginal Infections
A systematic review identified Stachys lavandulifolia as an Iranian medicinal plant with anti-vaginal infection properties [PMID:35490427]
Safety & adverse effects
Aqueous extract was found to have no significant hematological changes or mortality in sub-chronic toxicity studies in rats [PMID:25657785]. However, there are concerns regarding the potential pro-oxidant action of antioxidant supplementation [PMID:24027670].
Pregnancy & lactation
In pregnant mice, hydroalcoholic extracts caused a significant increase in absorbed fetuses and decreased fetus length and weight, suggesting potential abortifacient effects [PMID:27418911].
Evidence summary
Evidence consists of a mix of preclinical animal studies (mice/rats), in vitro cancer cell line research, and small-scale clinical trials. While traditional use is widespread, high-level clinical evidence (meta-analyses/large RCTs) is limited.
PubMed sources
1.PMID: 26734474 (2015) — Stachys lavandulifolia Vahl. and its Relation With Marmazad Activities in Traditional Manuscripts. · Iranian Red Crescent medical journal
2.PMID: 37061348 (2023) — Effect of stachys lavandulifolia on occupational stress in emergency medical technicians. · Explore (New York, N.Y.)
3.PMID: 38189318 (2024) — Botanical description, phytochemical constituents, ethnobotany, traditional medicinal use, and pharmacological activities of Stachys lavandulifolia Vahl. · Natural product research
4.PMID: 40899416 (2025) — Pharmacological and toxicological profile of the Stachys lavandulifolia Vahl: a comprehensive review. · Zeitschrift fur Naturforschung. C, Journal of biosciences
5.PMID: 35490427 (2022) — Native Iranian Medicinal Plants with Anti-Vaginal Infection Properties: A Systematic Review.
Government sources
No direct government monograph is available for this herb. The content below is AI-generated and has not been verified against an authoritative government source. Use the search links to check official sources before relying on this information.
6.PMID: 41104247 (2025) — Anti-proliferative Activity and Apoptosis Induction of Extracts and Fractions of Stachys lavandulifolia on Lung (H1299), Ovarian (A2780) and Breast (MCF-7) Human Cancer Cell Lines. · Iranian journal of pharmaceutical research : IJPR
7.PMID: 36589024 (2022) — Effect of Hydroalcoholic Extract of Stachys lavandulifolia on Pentylenetetrazole-induced Seizures in Male Mice: The Role of GABAergic and Opioidergic Systems. · Basic and clinical neuroscience
8.PMID: 14611891 (2003) — Anxiolytic effects of Stachys lavandulifolia Vahl on the elevated plus-maze model of anxiety in mice. · Journal of ethnopharmacology
9.PMID: 40400719 (2025) — Investigating the effect aerials part of Stachys Lavandulifolia ointment on 2nd degree burns compared to silver sulfadiazine on male rat. · International journal of burns and trauma
10.PMID: 20738162 (2010) — Extended longevity of Drosophila melanogaster by water and ethanol extracts of Stachys lavandulifolia. · Pharmaceutical biology
11.PMID: 23593591 (2013) — Phytochemical composition of the essential oil of different populations of Stachys lavandulifolia Vahl. · Asian Pacific journal of tropical biomedicine
12.PMID: 34026076 (2021) — A comparative study: Influence of various drying methods on essential oil components and biological properties of Stachys lavandulifolia. · Food science & nutrition
13.PMID: 25657785 (2014) — Acute and subchronic toxicological evaluation of Stachys lavandulifolia aqueous extract in Wistar rats. · Research in pharmaceutical sciences
14.PMID: 29853127 (2018) — In situ green synthesis of Ag nanoparticles on herbal tea extract (Stachys lavandulifolia)-modified magnetic iron oxide nanoparticles as antibacterial agent and their 4-nitrophenol catalytic reduction activity. · Materials science & engineering. C, Materials for biological applications
15.PMID: 29741912 (2018) — Therapeutic Effects of Standardized Formulation of Stachys lavandulifolia Vahl on Primary Dysmenorrhea: A Randomized, Double-Blind, Crossover, Placebo-Controlled Pilot Study. · Journal of alternative and complementary medicine (New York, N.Y.)
16.PMID: 23074920 (2012) — Antimicrobial and antioxidant activities of Stachys lavandulifolia subsp. lavandulifolia essential oil and its infusion. · Natural product communications
17.PMID: 40993927 (2025) — Network Pharmacology Integrated Molecular Docking Analysis Identifies Potential Phytochemicals in Stachys lavandulifolia against Polycystic Ovary Syndrome. · Current pharmaceutical design
18.PMID: 27418911 (2012) — The effect of hydroalcoholic extract of Stachys lavandulifolia vahl on pregnant mice. · EXCLI journal
19.PMID: 29844776 (2017) — Isolation and Identification of Secondary Metabolites from the Aerial Parts of Stachys lavandulifolia Vahl. · Iranian journal of pharmaceutical research : IJPR
20.PMID: 37505651 (2023) — Potent In Vitro and In Vivo Effects of Stachys lavandulifolia Methanolic Extract against Toxoplasma gondii Infection. · Tropical medicine and infectious disease
21.PMID: 24027670 (2013) — Comment on: Anti-Oxidative Stress Activity of Stachys lavandulifolia Aqueous Extract in Humans. · Cell journal
22.PMID: 24250359 (2011) — Spasmolytic effect of stachys lavandulifolia vahl. Crude methanolic extract and fractions on rat ileum. · Iranian journal of pharmaceutical research : IJPR