PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanolic extract showed gastroprotective effects against piroxicam-induced stomach lesions in Wistar rats [PMID:37869918]
S. media extract (40 µg/mL) provided neuroprotection against oxygen and glucose deficiency-induced mitochondrial impairment in rat hippocampal and cortical slices [PMID:35280571]
In vitro treatment (30 µg/mL) effectively suppressed the secretion of HBsAg and HBeAg in HepG2.2.15 cells [PMID:22810196]
S. media tea protected against cardiac dysfunction in diabetic rats, although it did not significantly affect fasting hyperglycemia or glucose intolerance [PMID:35493309]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 27189173 (2016) — Novel strong promoter of antimicrobial peptides gene pro-SmAMP2 from chickweed (Stellaria media). · BMC biotechnology
- 2.PMID: 39620022 (2024) — Small Steps to the Big Picture for Health-Promoting Applications Through the Use of Chickweed (Stellaria media): In Vitro, In Silico, and Pharmacological Network Approaches. · Food science & nutrition
- 3.PMID: 35493309 (2022) — Stellaria media tea protects against diabetes-induced cardiac dysfunction in rats without affecting glucose tolerance. · Journal of traditional and complementary medicine
- 4.PMID: 32047525 (2020) — Effect of Stellaria media Tea on Lipid Profile in Rats. · Evidence-based complementary and alternative medicine : eCAM
- 5.PMID: 32548330