PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Supplementation of 3g/day for 12 weeks significantly reduced appetite scores, serum leptin, neuropeptide Y (NPY), insulin, fasting blood sugar (FBS), and HOMA-IR [PMID:36753796]
A meta-analysis of 6 clinical trials suggested no significant effects on fasting blood glucose or glycosylated hemoglobin (HbA1c) [PMID:34365008]
A systematic review and dose-response meta-analysis of 7 RCTs demonstrated a significant reduction in high-sensitivity C-reactive protein (hs-CRP) concentrations in adults [PMID:41069418]
Participants consuming sumac juice showed a significantly smaller increase in pain scores during and after intense aerobic exercise compared to placebo [PMID:28639865]
A double-blind RCT of 1000 mg/day for two months found no significant difference between sumac and placebo in mean reductions of total cholesterol, LDL, or triglycerides [PMID:27840476]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 33430013 (2021) — Pharmacological and Antioxidant Activities of Rhus coriaria L. (Sumac). · Antioxidants (Basel, Switzerland)
- 2.PMID: 36014419 (2022) — Rhus coriaria L. (Sumac), a Versatile and Resourceful Food Spice with Cornucopia of Polyphenols. · Molecules (Basel, Switzerland)
- 3.PMID: 32141706 (2020) — Phytochemical Diversity and Pharmacological Properties of Rhus coriaria. · Chemistry & biodiversity
- 4.PMID: 38231844 (2023) — Phytochemical Investigation of Sumac (Rhus coriaria L.) Fruits from Different Sicilian Accessions. · Foods (Basel, Switzerland)
- 5.PMID: 34365008 (2021) — The effect of sumac (Rhus coriaria L.) supplementation on glycemic indices: A systematic review and meta-analysis of controlled clinical trials.