PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanolic extract (50-200 mg/kg) in rats ameliorated cisplatin-induced oxidative damage in renal, hepatic, and testicular tissues, restoring tissue morphology and increasing Bcl-2/Bax ratio [PMID:29746935]
Aqueous and ethanolic aerial part extracts (400 and 600 mg/kg) significantly increased the latency to first minimal clonic seizures and generalized tonic-clonic seizures in mice [PMID:27462553]
Nanoliposomal essential oil demonstrated significant antibacterial activity against E. coli, P. aeruginosa, and S. aureus with MIC values ranging from 2.59 to 5.187 μg/μL [PMID:38835158]
Root methanol and herb water extracts exhibited strong α-glucosidase inhibitory activity (69.88% and 71.23% respectively) at 100 μg/mL [PMID:40953089]
Hydroalcoholic extracts showed anti-leishmanial activity against Leishmania major promastigotes with an IC50 of 298.42 μg/ml at 72h [PMID:27876985]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37554989 (2023) — A comprehensive review of summer savory (Satureja hortensis L.): promising ingredient for production of functional foods. · Frontiers in pharmacology
- 2.PMID: 30257512 (2018) — Phytochemical Profile and Biological Activities of Satureja hortensis L.: A Review of the Last Decade. · Molecules (Basel, Switzerland)
- 3.PMID: 36743952 (2023) — Effects of summer savory (Satureja hortensis L.) and sweet corn (Zea mays L. saccharata) intercropping on crop production and essential oil profiles of summer savory. · PeerJ
- 4.PMID: 35214866 (2022) — Flavonoid Accumulation in an Aseptic Culture of Summer Savory (Satureja hortensis L.). · Plants (Basel, Switzerland)
- 5.PMID: 33466256 (2021)