PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Oral administration of Helianthus annuus leaf extract (not seed) was found to ameliorate atopic dermatitis in mice by suppressing T cell activity and abrogating IL-2 production [PMID: 36108372]
Sunflower seed byproduct ethanol extract (HSE) demonstrated a preventive effect against ultraviolet radiation-induced injury in human keratinocytes and fibroblasts by inhibiting ROS production [PMID: 37727996]
Sunflower seed extracts showed antimicrobial properties, most effectively against E. coli, with a 3g dosage producing an average zone of inhibition of 12 mm [PMID: 35564857]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 38085525 (2025) — Sunflower (Helianthus annuus) Seed Allergy. · Journal of investigational allergology & clinical immunology
- 2.PMID: 36994824 (2023) — Safety Assessment of Helianthus annuus (Sunflower)-Derived Ingredients as Used in Cosmetics. · International journal of toxicology
- 3.PMID: 36108372 (2022) — Oral administration of Helianthus annuus leaf extract ameliorates atopic dermatitis by modulation of T cell activity in vivo. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 4.PMID: 29086881 (2017) — A review of phytochemistry, metabolite changes, and medicinal uses of the common sunflower seed and sprouts (Helianthus annuus L.). · Chemistry Central journal
- 5.PMID: 38301931