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Comptonia peregrina
Aromatic shrub of eastern North American dry woods; used by many Indigenous peoples for diarrhea, wound healing and insect repellent.
Aromatic shrub of eastern North American dry woods; used by many Indigenous peoples for diarrhea, wound healing and insect repellent. Key active compounds include myricadiol, catechins, tannins.
myricadiol, along with catechins and tannins, are the primary bioactive compounds in Sweet Fern. These compounds modulates NF-κB and COX-2 inflammatory pathways, promotes tissue regeneration and modulates local inflammation.
Astringent
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Wound healing
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Insect repellent
Anti-inflammatory
Diarrhea and dysentery by Abenaki and other tribes
Based on traditional use; clinical evidence limited
Wound healing and skin conditions
Based on traditional use; clinical evidence limited
Insect repellent use
Based on traditional use; clinical evidence limited
Smoke fumigant for insects
Based on traditional use; clinical evidence limited
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