PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 17 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Clinical evidence
A 30-60 min hydrodistillation fraction of leaf essential oil demonstrated cytotoxic activity against human lung carcinoma (A-549) and human colon adenocarcinoma (DLD-1) cell lines [PMID:17326040].
The phenolic stilbene (E)-3-hydroxy-5-methoxystilbene isolated from leaves showed inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium bovis BCG, and avirulent Bacillus anthracis [PMID:18849164].
Essential oils exerted significant dose- and time-dependent repellent activity towards Ixodes scapularis nymphs and reduced attraction of adult I. scapularis and D. variabilis ticks [PMID:41619107].
Evidence summary
PubMed sources
- 1.PMID: 41619107 (2026) — Efficacy of a novel tick attractant and repellent activity of essential oils from sweet fern, Comptonia peregrina (L.) Coult. · Experimental & applied acarology
- 2.PMID: 31877179 (2019) — Lowbush blueberry fruit yield and growth response to inorganic and organic N-fertilization when competing with two common weed species. · PloS one
- 3.PMID: 36138805 (2022) — A New Species of Comptonia (Myricaceae) from the Early Miocene of Central Inner Mongolia, China, and Phytogeographic History of Sweet-Fern. · Biology
- 4.PMID: 17757592 (1978) — Isolation and Cultivation in vitro of the Actinomycete Causing Root Nodulation in Comptonia. · Science (New York, N.Y.)
- 5.PMID: 23195863 (1985)