PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Rhizome extract (TCE) alleviated scopolamine-induced cognitive impairment and neuroinflammation in rats [PMID:40458441]
Taccalonolides and evelynin exhibited cytotoxic activity against multiple human cancer cell lines, including breast, prostate, and cervical carcinoma [PMID:20715765, PMID:25679147, PMID:18974132]
Extracts showed cytotoxic effects on KKU-213A and KKU-213C cell lines and enhanced cisplatin sensitivity [PMID:39820585]
Certain isolates (chantriolides F-P) significantly enhanced viability of t-BHP-injured AML12 hepatocytes [PMID:36500291]
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 34581038 (2021) — [Research on anti-tumor natural product diosgenin]. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- 2.PMID: 33253561 (2020) — Neuroprotective and Anti-inflammatory Ditetrahydrofuran-Containing Diarylheptanoids from Tacca chantrieri. · Journal of natural products
- 3.PMID: 36500291 (2022) — Chantriolides F-P, Highly Oxidized Withanolides with Hepatoprotective Activity from Tacca chantrieri. · Molecules (Basel, Switzerland)
- 4.PMID: 40458441 (2025) — Tacca chantrieri André Rhizome Extract Alleviates Scopolamine-Induced Cognitive Impairment and Neuroinflammation in Rats. · Advances in pharmacological and pharmaceutical sciences
- 5.PMID: 25679147