PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Polysaccharides (PH-PS) ameliorated learning and spatial memory deficits and reduced amyloid β build-up [PMID:38750854]
Heterophyllin B improved functional recovery by promoting axonal regeneration and reducing neuroinflammation [PMID:39494322]
Polysaccharides (PHP) improved blood perfusion and microvessel density [PMID:41005057]
Aqueous extract (AEPH) ameliorated colorectal cancer by remodeling the tumor immune microenvironment [PMID:39828144]
PHP significantly increased average daily gain, total protein, albumin, insulin, thyroxine, and growth hormone [PMID:37931159]
Evidence summary
PubMed sources
- 1.PMID: 31139247 (2019) — Chemistry, pharmacology and analysis of Pseudostellaria heterophylla: a mini-review. · Chinese medicine
- 2.PMID: 41005057 (2025) — Pseudostellaria heterophylla polysaccharides attenuate diabetic lower limb ischemia via CYP2E1-mediated mitochondrial homeostasis and PANoptosis regulation. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 3.PMID: 35432244 (2022) — Pathogen-Mediated Assembly of Plant-Beneficial Bacteria to Alleviate Fusarium Wilt in Pseudostellaria heterophylla. · Frontiers in microbiology
- 4.PMID: 32529767 (2020) — Rapid authentication of Pseudostellaria heterophylla (Taizishen) from different regions by near-infrared spectroscopy combined with chemometric methods. · Journal of food science
- 5.PMID: 38391514