PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Oral administration of A. acutiloba root extract (300 mg/kg/day) in rats fed a high-fructose diet reduced HOMA-IR and elevated ISIcomp, showing effects similar to pioglitazone [PMID: 21308821]
Oral administration of Angelica root in rats increased hippocampal acetylcholine levels, prevented apoptosis, and improved memory in a radial maze task [PMID: 29269276]
Oral administration of AAK extract (500 mg/kg/day) in DSS-induced murine colitis significantly alleviated weight loss, diarrhea, bloody stools, and colon shortening [PMID: 27293323]
Oral administration of an ethanol extract of Yamato Toki (200 mg) significantly increased blood flow in the hind paw of stroke-prone spontaneously hypertensive rats [PMID: 30549606]
Fractions of Angelica acutiloba (specifically the butanol layer containing N-methyl-beta-carboline-3-carboxamide and amines) increased correct choices in scopolamine-induced memory impairment in rats [PMID: 15351791]
Evidence summary
PubMed sources
- 1.PMID: 37581741 (2023) — Population genetic structure of wild Angelica acutiloba, A. acutiloba var. iwatensis, and their hybrids by atpF-atpA intergenic spacer in chloroplast DNA and genome-wide SNP analysis using MIG-seq. · Journal of natural medicines
- 2.PMID: 34622386 (2022) — Efficient fertilization in the cultivation of Angelica acutiloba (Siebold & Zucc.) Kitag. in Hokkaido: Effect of amount of supplied nitrogen on growth, yield, and quality of A. acutiloba. · Journal of natural medicines
- 3.PMID: 33686489 (2021) — Studies on cultivation of Angelica acutiloba using paper pot (Part 2): effect of difference in taproot base diameter of seedlings on growth after planting and quality of toki produced from paper pot seedlings. · Journal of natural medicines
- 4.PMID: 20527290 (2009) — [History and the present of cultivation and production of Angelica root, Yamato-Toki, in Japan]. · Yakushigaku zasshi
- 5.