PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 24 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
In vitro, Dipsacus fullonum leaf extract and specifically the iridoid-glycoside fraction (sylvestrosides III and IV) showed high anti-Borrelia activity with reduced cytotoxicity [PMID:35056144].
Bushen Qiangdu Recipe, which includes teasel root, was evaluated for its therapeutic effect on bone mineral density and disease activity indices in patients with ankylosing spondylitis [PMID:21608215].
Zhichan powder (containing himalayan teasel root) diminished the expression of pro-apoptotic markers (TNF receptor 1, Fas, caspase-8, cytochrome C, Bax, caspase-3, p53) and increased Bcl-2 expression in the substantia nigra of rats [PMID:25558224].
Evidence summary
PubMed sources
- 1.PMID: 35868154 (2022) — Extraction of bioactive compounds from Dipsacus fullonum leaves using deep eutectic solvents. · Journal of chromatography. A
- 2.PMID: 31936189 (2020) — Roots and Leaf Extracts of Dipsacus fullonum L. and Their Biological Activities. · Plants (Basel, Switzerland)
- 3.PMID: 35056144 (2022) — Extraction and Fractionation of Bioactives from Dipsacus fullonum L. Leaves and Evaluation of Their Anti-Borrelia Activity. · Pharmaceuticals (Basel, Switzerland)
- 4.PMID: 21445274 (2011) — Carnivory in the teasel Dipsacus fullonum--the effect of experimental feeding on growth and seed set. · PloS one
- 5.PMID: 28328952 (2017) — Understanding the unique flowering sequence in Dipsacus fullonum: Evidence from geometrical changes during head development.