PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Flower extract (1000 mg/kg) showed anti-inflammatory activity in Wistar rats [PMID:32981250]; inflorescence extract mitigated acute gastric ulcers by suppressing iNOS expression [PMID:40547510].
Flower aqueous extract (1000 mg/kg) protected against oxidative stress-induced nephropathy in type 2 diabetic rats [PMID:35502173]; ethanol extract improved systolic blood pressure, plasma creatinine, and plasma glucose in mice with hypertension and diabetes [PMID:36464492].
70% ethanolic flower extract affected cyclooxygenase-2 (COX-2) expression in the gingival epithelium of rat models [PMID:39885945].
Extracts showed protective effects against lead acetate-induced hepatotoxicity [PMID:20930461], bone marrow oxidative stress [PMID:20600524], and testicular damage [PMID:22969852] in rats.
Extracts displayed cytotoxicity to B16F10 melanoma cells [PMID:37959789] and promoted cell death via down-regulation of ERK and Akt signaling [PMID:28830513].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 41494611 (2026) — Trends and multidisciplinary research of torch ginger [Etlingera elatior (Jack) R.M.Sm.]: A systematic review. · Journal of ethnopharmacology
- 2.PMID: 32981250 (2020) — Anti-inflammatory Activity of Etlingera elatior (Jack) R.M. Smith Flower on Gastric Ulceration-induced Wistar Rats. · Pakistan journal of biological sciences : PJBS
- 3.PMID: 39885945 (2024) — Effects of Etlingera elatior flower extract on cyclooxygenase-2 expression in the gingival epithelium in a diabetic periodontitis rat model. · Journal of Taibah University Medical Sciences
- 4.PMID: 30311471 (2018) — Torch Ginger (Etlingera elatior): A Review on its Botanical Aspects, Phytoconstituents and Pharmacological Activities. · Pakistan journal of biological sciences : PJBS
- 5.PMID: 37304615