PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A randomized, double-blind, placebo-controlled trial was conducted to determine the effectiveness of tormentil root extract for treatment [PMID:12913771].
A combination of tormentil, menthol, raspberry leaves, and loosestrife alleviated diarrheal symptoms in diseased mice; tormentil and menthol alone reduced colonic T cell numbers [PMID:37896170].
A 400 mg/kg dose of tormentil extract significantly decreased experimental arterial thrombosis [PMID:28860991].
A 100 mg/kg dose decreased thrombus area in mice via antiplatelet effects, but a 200 mg/kg dose increased thrombus weight in rats [PMID:34025439].
Tormentil has been tested or intended for the treatment of atopic dermatitis and rosacea [PMID:32046246].
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 37896170 (2023) — Therapeutic Effects of Oral Application of Menthol and Extracts from Tormentil (Potentilla erecta), Raspberry Leaves (Rubus idaeus), and Loosestrife (Lythrum salicaria) during Acute Murine Campylobacteriosis. · Pharmaceutics
- 2.PMID: 28860991 (2017) — Antithrombotic Potential of Tormentil Extract in Animal Models. · Frontiers in pharmacology
- 3.PMID: 19857087 (2009) — Determination of acute toxicity of the aqueous extract of Potentilla erecta (Tormentil) rhizomes in rats and mice. · Journal of medicinal food
- 4.PMID: 26047031 (2015) — Quantification of tannins and related polyphenols in commercial products of tormentil (Potentilla tormentilla). · Phytochemical analysis : PCA
- 5.PMID: 32046246