PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Oral administration of Dialium guineense pulp extract caused a dose-dependent significant decrease in the ulcer index in albino Wistar rats [PMID:34907760]
Fruit pulp administered at 1000, 2000, and 4000 mg/kg before induction significantly delayed diarrhea and reduced defecation frequency and purging index in Wistar rats, with inhibition comparable to loperamide [PMID:36317113]
Methanolic stem bark extract significantly decreased abdominal constriction in acetic acid-induced writhing models in mice in a dose-dependent fashion [PMID:23209955]
A dichloromethane fraction (DF-5) of the fruit coat showed wound healing properties in a full thickness skin excision model [PMID:27499791]
Phenolic extract of the pulp enhanced ROS detoxification and mitigated the decrease in activities of detoxifying enzymes (SOD, catalase, GPx, GR, and G6PD) in rat livers [PMID:24892362]
Evidence summary
PubMed sources
- 1.PMID: 25172748 (2015) — Key volatile aroma compounds of three black velvet tamarind (Dialium) fruit species. · Food chemistry
- 2.PMID: 34907760 (2021) — Protective effects of Dialium guineense pulp on aspirin-induced gastric mucosal injury in albino rats. · Journal of applied biomedicine
- 3.PMID: 36317113 (2022) — Antidiarrheal Activity of Dialium guineense Willd Fruit Pulp in Wistar Rats. · BioMed research international
- 4.PMID: 30632774 (2019) — Nutritional and medicinal properties of underexploited legume trees from West Africa. · Critical reviews in food science and nutrition
- 5.PMID: 23776811 (2012) — Antimicrobial potential of Dialium guineense (Wild.) stem bark on some clinical isolates in Nigeria.