PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 27 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A gel containing Viola tricolor flower extract showed antinociceptive and anti-inflammatory effects in a rat model of UVB-induced sunburn, reducing paw edema and neutrophilic cell infiltration [PMID:24008111]
Heartsease is identified as a medicinal plant with potential acne treatment properties, including antibacterial, anti-inflammatory, or sebum-reducing effects in vitro or clinically [PMID:41439563]
Hydroalcoholic extracts reduced cytotoxicity induced by serum/glucose deprivation in PC12 neuronal cells in vitro [PMID:27516984]
Infusions, decoctions, and ethanol extracts of the herb demonstrated antimicrobial activity against tested microorganisms [PMID:15893888]
Evidence summary
PubMed sources
- 1.PMID: 19007486 (2008) — Analysis of polar antioxidants in Heartsease (Viola tricolor L.) and Garden pansy (Viola x wittrockiana Gams.). · Journal of chromatographic science
- 2.PMID: 18366866 (2008) — Quantitative and qualitative investigation of the main flavonoids in heartsease (Viola tricolor L.). · Journal of chromatographic science
- 3.PMID: 41439563 (2026) — Medicinal Plants for Acne Vulgaris: An Evidence-Based Review of Treatments Promoted by Social Media. · Journal of cosmetic dermatology
- 4.PMID: 15893888 (2005) — Antimicrobial activity of Viola tricolor herb. · Fitoterapia
- 5.PMID: 18259733 (2008) — Major flavonoid components of heartsease (Viola tricolor L.) and their antioxidant activities.