PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
In mouse models of osteosarcoma and ovarian cancer, the thiolane-type sulfide onionin A1 depressed tumor proliferation and controlled metastasis by regulating macrophage activation [PMID:28250342]
Extract of Allium fistulosum roots was used in letrozole-induced PCOS rats to improve ovarian functions [PMID:30287740]
Ethanolic and aqueous extracts of A. fistulosum attenuated high-fat diet-induced obesity in male C57BL/6J mice [PMID:29558911]
Welsh onion extracts caused vasodilation on precontracted vessel rings in rat aortae [PMID:10218719]
A multi-center, randomized, double-blind, placebo-controlled trial evaluated the effects of WCO31 (A. fistulosum root and Avena sativa mixtures) on height growth and safety in children aged 6-8 years [PMID:42123928]
Evidence summary
PubMed sources
- 1.PMID: 28250342 (2017) — Antitumor Allium Sulfides. · Chemical & pharmaceutical bulletin
- 2.PMID: 35161326 (2022) — Welsh Onion (Allium fistulosum L.) Seed Physiology, Breeding, Production and Trade. · Plants (Basel, Switzerland)
- 3.PMID: 34081271 (2021) — Thiolane-type sulfides from garlic, onion, and Welsh onion. · Journal of natural medicines
- 4.PMID: 38137307 (2023) — Green Onion (Allium fistulosum): An Aromatic Vegetable Crop Esteemed for Food, Nutritional and Therapeutic Significance. · Foods (Basel, Switzerland)
- 5.PMID: 37622030 (2023) — The complete mitochondrial genome of Allium fistulosum L. (Amaryllidaceae).