PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 12 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanolic extracts of rhizomes containing C17 polyacetylenes demonstrate significant inhibitory activity against Mycobacterium tuberculosis strain H37Ra in vitro [PMID:22234257].
Hexane fractions from the rhizome (RH) and fruit (FH) showed selective cytotoxicity against human colon (WiDr), leukemia (Molt), and cervix (HELA) cancer cells in vitro, with lower toxicity toward normal human umbilical vein endothelial cells [PMID:16827159, PMID:17034664].
Phenolic extracts from rhizomes inhibit cellular oxidative stresses induced by UV-B and IR-A radiation [PMID:34361611].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 34361611 (2021) — Phenolic Extract from Aralia nudicaulis L. Rhizomes Inhibits Cellular Oxidative Stresses. · Molecules (Basel, Switzerland)
- 2.PMID: 22234257 (2012) — Anti-mycobacterial diynes from the Canadian medicinal plant Aralia nudicaulis. · Journal of ethnopharmacology
- 3.PMID: 16827159 (2006) — Anticancer effect of extracts from a North American medicinal plant--wild sarsaparilla. · Anticancer research
- 4.PMID: 20657619 (2010) — Antimycobacterial screening of traditional medicinal plants using the microplate resazurin assay. · Canadian journal of microbiology
- 5.PMID: 26669092 (2015) — Antimycobacterial Natural Products from Endophytes of the Medicinal Plant Aralia nudicaulis.