PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Extracts from roots and aerial parts showed antibacterial activity against Staphylococcus aureus, Cutibacterium acnes, and Bacillus cereus [PMID:34882948, PMID:29116480].
Root extracts exhibited antidiabetic activity in hen's egg test models and Drosophila melanogaster [PMID:34975489].
Methanolic extracts of root and aerial parts increased the expression of $\alpha$-actinin and cardiac troponin I (cTnI) in adipose-derived human mesenchymal stem cells [PMID:29687729].
Ethanolic extracts showed inhibitory activity against $\alpha$-Synuclein fibrillation [PMID:27353564] and exhibited scavenging effects against 2,2-diphenyl-1-picrylhydrazyl [PMID:26109755].
Ethyl acetate extract of aerial parts exhibited antineoplastic activity on bladder cancer cell lines by inducing apoptosis [PMID:35011479].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 39157738 (2023) — The genome sequence of wood avens, Geum urbanum L., 1753. · Wellcome open research
- 2.PMID: 34882948 (2022) — Evaluation of Geum urbanum L. Extracts with Respect to Their Antimicrobial Potential. · Chemistry & biodiversity
- 3.PMID: 41375170 (2025) — Ellagitannins and Other Polyphenols Along with Dietary Components of the Rosaceae Medicinal Plants. · Molecules (Basel, Switzerland)
- 4.PMID: 34203945 (2021) — Insight into the Secondary Metabolites of Geum urbanum L. and Geum rivale L. Seeds (Rosaceae). · Plants (Basel, Switzerland)
- 5.PMID: 34975489 (2021) — Avens Root (Geum Urbanum L.) Extract Discovered by Target-Based Screening Exhibits Antidiabetic Activity in the Hen's Egg Test Model and Drosophila melanogaster.