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Xanthorrhiza simplicissima
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
Small native American shrub with intensely yellow roots rich in berberine; folk remedy for mouth sores and ulcers.
Small native American shrub with intensely yellow roots rich in berberine; folk remedy for mouth sores and ulcers. Key active compounds include berberine, magnoflorine, jateorhizine.
berberine, along with magnoflorine and jateorhizine, are the primary bioactive compounds in Xanthorrhiza simplicissima. These compounds modulates NF-κB and COX-2 inflammatory pathways, disrupts microbial cell membranes and inhibits pathogen growth, promotes tissue regeneration and modulates local inflammation.
Antimicrobial
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Anti-inflammatory
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Bitter tonic
Wound healing
Mouth ulcers
Based on traditional use; clinical evidence limited
Sore throat
Based on traditional use; clinical evidence limited
Digestive aid
Based on traditional use; clinical evidence limited
Liver
Based on traditional use; clinical evidence limited
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