PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ma-Huang-Fu-Zi-Xi-Xin decoction was evaluated for treatment effects and safety in a meta-analysis of 6 RCTs involving 576 participants [PMID: 29636787]. Essential oil (AEO) significantly reduced nasal secretions and sneezing in rat models [PMID: 32395767].
Essential oil (AEO) inhibited the increase in epithelial thickness and decreased collagen deposition in lung tissues of OVA+PM10-challenged mice [PMID: 35335934].
Water extracts demonstrated strong analgesic properties in acute thermal, mechanical, and chronic inflammatory pain models in mice [PMID: 38154768].
Ethanol and aqueous extracts inhibited the growth, acid production, and adherence of Streptococcus mutans [PMID: 17201637].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 29636787 (2018) — Ma-Huang-Fu-Zi-Xi-Xin Decoction for Allergic Rhinitis: A Systematic Review. · Evidence-based complementary and alternative medicine : eCAM
- 2.PMID: 40328202 (2025) — Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health. · International dental journal
- 3.PMID: 39521103 (2025) — The essential oils from Asarum sieboldii Miq. Alleviate allergic rhinitis by regulating tight junction and inflammation; Network analysis and preclinical validation. · Journal of ethnopharmacology
- 4.PMID: 37355024 (2023) — Phytochemical investigation of Asarum sieboldii var. seoulense and the phenotypic profiles of its constituents against a Parkinson's Disease olfactory cell line. · Bioorganic & medicinal chemistry letters
- 5.PMID: 35244949