PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Moderate intake in healthy and hypercholesterolemic subjects decreased blood pressure, inflammatory cytokines, chemokines, and LDL-C [PMID:40263915].
Consumption is associated with significantly higher lumbar spine, femoral neck, and total hip bone mineral density in postmenopausal women, with a lower frequency of osteoporosis diagnosis [PMID:21920487, PMID:40537107].
Supplementation may be helpful in reducing body weight and fat [PMID:26408319]; reviews suggest it may improve lipid parameters and counteract obesity-related inflammation [PMID:25621503].
Administration of 5 g/day for 6 weeks improved microcirculatory parameters in volunteers with high blood viscosity [PMID:25562195].
A systematic review and meta-analysis evaluated lipid-lowering properties, though results were noted as conflicting [PMID:39666845].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 36647770 (2023) — Physiological effects of yerba maté (Ilex paraguariensis): a systematic review. · Nutrition reviews
- 2.PMID: 18034743 (2007) — Yerba Mate Tea (Ilex paraguariensis): a comprehensive review on chemistry, health implications, and technological considerations. · Journal of food science
- 3.PMID: 39666845 (2012) — Effect of Yerba Mate (Ilex paraguariensis) on Lipid Levels: A Systematic Review and Meta-Analysis. · Plant foods for human nutrition (Dordrecht, Netherlands)
- 4.PMID: 41470797 (2025) — Yerba Mate (Ilex paraguariensis) and Rheumatoid Arthritis: A Systematic Review of Mechanistic and Clinical Evidence. · Nutrients
- 5.PMID: 36180970 (2023)