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Multi-herb Kampo formula
Japanese Kampo formula studied for dementia agitation and insomnia.
Japanese Kampo formula studied for dementia agitation and insomnia. Key active compounds include Geissoschizine methyl ether, Atractylenolide, Glycyrrhizin.
Geissoschizine methyl ether, along with Atractylenolide and Glycyrrhizin, are the primary bioactive compounds in Kampo Yokukansan. The specific pharmacological pathways require further study, though traditional use supports its efficacy.
5-HT1A agonist
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Glutamate modulator
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Anxiolytic
Irritability
Based on traditional use; clinical evidence limited
Insomnia
Based on traditional use; clinical evidence limited
Childhood night crying
Based on traditional use; clinical evidence limited
Dementia agitation
Based on traditional use; clinical evidence limited
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