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Zanthoxylum chalybeum
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
Spiny East African tree used across Uganda, Kenya, and Tanzania for malaria, sexually transmitted infections, rheumatism, and as a tonic.
Spiny East African tree used across Uganda, Kenya, and Tanzania for malaria, sexually transmitted infections, rheumatism, and as a tonic. Key active compounds include chelerythrine, berberine, lupeol.
chelerythrine, along with berberine and lupeol, are the primary bioactive compounds in Zanthoxylum Chalybeum. These compounds modulates NF-κB and COX-2 inflammatory pathways, disrupts microbial cell membranes and inhibits pathogen growth, acts on pain pathways via anti-inflammatory and neuroactive effects.
Antimicrobial activity
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Antimalarial effects
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Anti-inflammatory properties
Analgesic action
Malaria treatment
Based on traditional use; clinical evidence limited
STI treatment
Based on traditional use; clinical evidence limited
Rheumatic pain
Based on traditional use; clinical evidence limited
Fever reduction
Based on traditional use; clinical evidence limited
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