Berberine Source vs Xanthorrhiza simplicissima

Side-by-side comparison of medicinal herbs

Herb

Berberine Source

Berberis aquifolium

Antimicrobial

Xanthorrhiza simplicissima

Antimicrobial

⚠️ Pregnancy & Nursing Warnings

Berberine Source

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Xanthorrhiza simplicissima

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Description

The Pacific Northwest species containing berberine; antimicrobial activity comparable to tetracycline for GI infections; antiprotozoal against Giardia and Candida.

Small native American shrub with intensely yellow roots rich in berberine; folk remedy for mouth sores and ulcers.

Active Compounds

Berberine, Berbamine, Oxyacanthine, Columbamine

berberine, magnoflorine, jateorhizine, columbamine

Traditional Uses

Liver and digestive support in Native American medicine, Skin diseases and psoriasis, Antimicrobial for intestinal infections

mouth ulcers, sore throat, bitter tonic, digestive aid, liver

Modern Uses

Antimicrobial for GI infections (berberine), Psoriasis and skin inflammation, Anti-diabetic via berberine

antimicrobial, anti-inflammatory, bitter tonic, wound healing

Adult Dosage

500mg root extract three times daily

1-2ml tincture or 1-2g root daily

Contraindications

Avoid with neonates, Avoid in pregnancy

pregnancy, neonates

Side Effects

GI disturbance, Constipation

GI upset, generally safe at low doses

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E

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