Butterbur vs Angelica dahurica

Butterbur is a perennial plant native to Europe and parts of Asia, used since ancient times for plague, fever, and respiratory conditions. Modern clinical trials have established it as an effective treatment for migraine prevention and allergic rhinitis. Only PA-free (pyrrolizidine alkaloid-free) products should be used.

TCM exterior-releasing herb for wind-cold conditions with headache; opens nasal passages.

Petasin, Isopetasin, Oxopetasin, Flavonoids, Sesquiterpenes

byakangelicin, isoimperatorin, phellopterin, xanthotoxin, bergapten, columbianetin

Plague treatment, Fever reduction, Headache relief, Respiratory support, Antispasmodic

headache, toothache, nasal congestion, rhinitis, skin conditions

Migraine prevention, Allergic rhinitis (hay fever), Asthma, Headache prevention, Urinary spasms

analgesic, anti-inflammatory, antipyretic, antimicrobial

50-75mg PA-free extract twice daily for migraines

3-9g dried root or 300mg extract daily

Liver disease, Allergy to ragweed or daisy family, Pregnancy, Non-PA-free products (liver toxicity)

yin deficiency heat, fire excess headache, pregnancy large doses

GI upset, Belching, Headache, Fatigue, Liver damage (from PA-containing products)

photosensitivity, GI upset