Griffonia Simplicifolia vs Albizia

A West African climbing shrub whose seeds contain 5-HTP (5-hydroxytryptophan), the direct precursor to serotonin; clinically effective for depression, anxiety, insomnia, and appetite control.

Called the "tree of happiness" in TCM, its bark and flowers are used for depression, anxiety, and insomnia.

5-HTP (5-hydroxytryptophan), Griffonin, Benzylamine derivatives

Saponins (julibrosides), Flavonoids, Tannins, Lignan glycosides

Mood enhancement and anti-depressant in West African folk medicine, Appetite control in traditional use, Sleep support

Depression, Anxiety, Insomnia, Trauma/grief

Depression and anxiety (5-HTP precursor to serotonin), Insomnia and sleep quality, Appetite suppression for weight management

Anxiolytic, Antidepressant-like, Sedative, Anti-inflammatory

100-300mg 5-HTP standardized extract twice daily

6-15g dried bark in decoction or 3-5g flowers as tea

CONTRAINDICATED with SSRIs MAOIs and serotonin agents, Avoid with carbidopa, Serotonin syndrome risk

Pregnancy, Sedative medications

Nausea, GI disturbance, Serotonin syndrome with antidepressants

Drowsiness, GI upset