Herb Paris vs Hypericum Maculatum

European woodland plant with highly toxic berries used historically in European folk medicine for nervous conditions and as an antidote.

Perennial herb of European meadows closely related to common St John's Wort, used in Central European folk medicine for similar nervous system conditions.

paristyphnin, paridine, saponins, steroidal glycosides, alkaloids

hypericin, pseudohypericin, hyperforin, flavonoids, xanthones

Nervous conditions and spasm historically in European folk medicine, Eye conditions topically in medieval practice, Antidote to poisons historically, Wound healing

mild depression, nervous conditions, wound healing, anxiety, neuralgia

Antispasmodic research, Cytotoxic research

antidepressant, anxiolytic, wound healing, anti-inflammatory

Homeopathic preparations only; any crude use extremely dangerous

4–6g dried herb as tea 3x daily or 300mg extract

Internal use without expert supervision, Pregnancy, All forms except homeopathic

SSRIs, cyclosporine, contraceptives, pregnancy, photosensitivity

Severe toxicity with crude preparations, Vomiting, Convulsions, Cardiac failure

photosensitivity, serotonin syndrome, drug interactions