Life Root vs Abuta Grandifolia

Side-by-side comparison of medicinal herbs

Herb

Life Root

Packera aurea

Womens Health

Abuta grandifolia

Womens Health

Life Root

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Abuta Grandifolia

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Description

Eastern North American groundsel used by many Native American nations as a uterine tonic and women's herb, with pyrrolizidine alkaloid cautions.

Woody vine of the Amazon used by indigenous peoples and traditional midwives for female reproductive conditions, pain management, and fever.

Active Compounds

senecionine, integerrimine, florosenine, flavonoids, tannins

hayatinin, cissampeline, berberine, alkaloids, flavonoids

Traditional Uses

Uterine tonic in Cherokee and Menominee women's medicine, Menstrual regulation and amenorrhea, Post-partum recovery, Urinary conditions

menstrual disorders, childbirth support, fever, pain, urinary conditions

Modern Uses

Uterine stimulant, Emmenagogue, Diuretic, Astringent

antispasmodic, anti-inflammatory, analgesic, diuretic

Adult Dosage

0.5-1ml tincture twice daily maximum (short term only due to pyrrolizidine alkaloids)

2–4g bark or leaf tea or 30 drops tincture 3x daily

Contraindications

Pregnancy, Liver disease, Prolonged use due to pyrrolizidine alkaloids

pregnancy (uterotonic at high doses), anticoagulants, children

Side Effects

Hepatotoxicity with prolonged use, Veno-occlusive liver disease

nausea, uterine contractions

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E