Sassafras vs Zygophyllum fabago

Side-by-side comparison of medicinal herbs

Herb

Sassafras

Sassafras albidum

Anti-inflammatory

Anti-inflammatory

Sassafras

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Zygophyllum fabago

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Description

A Native American tree that was once the second largest export from the New World, now controversial due to safrole content.

Middle Eastern and Central Asian succulent herb used in traditional medicine for inflammation and skin conditions.

Active Compounds

Safrole, Camphor, Asarone, Tannins

rutin, kaempferol, flavonoids, saponins, alkaloids

Traditional Uses

Blood purification, Skin conditions, Rheumatism, STIs

inflammation, skin conditions, rheumatism, fever

Modern Uses

Anti-inflammatory (safrole-free extracts), Diaphoretic, Historically significant

anti-inflammatory, antioxidant, antipyretic

Adult Dosage

CAUTION: Safrole is a carcinogen. Only safrole-free extracts. Short-term use.

3-5g dried herb tea 2x/day

Contraindications

Pregnancy, Liver disease, Cancer, Long-term use

pregnancy

Side Effects

Hepatotoxicity, Carcinogenicity (safrole), Dermatitis

GI upset

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E