St. John's Wort vs Hypericum olympicum

St. John's Wort is a flowering plant that has been used medicinally since ancient Greece. It is best known for its use in treating mild to moderate depression, where clinical evidence supports its efficacy comparable to some conventional antidepressants. It is named for its traditional harvest on St. John's Day.

Greek mountain Hypericum; used in traditional Greek medicine similar to H. perforatum.

Hypericin, Hyperforin, Adhyperforin, Flavonoids, Xanthones

hypericin, pseudohypericin, hyperforin, rutin, flavonoids

Depression treatment, Wound healing, Nerve pain relief, Anti-inflammatory, Sedative

depression, wound healing, nerve pain

Mild to moderate depression, Seasonal affective disorder, Anxiety, Nerve pain, Menopausal symptoms

antidepressant, anti-inflammatory, antimicrobial

300mg extract (0.3% hypericin) 3 times daily

2-4g dried herb or 1-2ml tincture daily

Concurrent use with SSRIs or MAOIs, Bipolar disorder, Schizophrenia, Organ transplant recipients, HIV patients on antiretrovirals

antidepressants, photosensitivity, contraceptives

Photosensitivity, Dry mouth, Dizziness, GI upset, Fatigue, Restlessness