Loading...
This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Loading...
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before using herbs, especially if you are pregnant, nursing, taking medications, or have a medical condition.
Hypericum perforatum
St. John's Wort is a flowering plant that has been used medicinally since ancient Greece. It is best known for its use in treating mild to moderate depression, where clinical evidence supports its efficacy comparable to some conventional antidepressants. It is named for its traditional harvest on St. John's Day.
St. John's Wort (Hypericum perforatum) is the most extensively studied botanical antidepressant, with Level A evidence for mild to moderate depression. Standardized extracts (0.3% hypericin, 2-4% hyperforin) demonstrate efficacy comparable to SSRIs.
Hyperforin inhibits serotonin, norepinephrine, and dopamine reuptake non-competitively. Also modulates NMDA receptors. St. John's Wort is a potent CYP3A4 and P-glycoprotein inducer, explaining many drug interactions.
St. John's Wort is a flowering plant that has been used medicinally since ancient Greece. It is best known for its use in treating mild to moderate depression, where clinical evidence supports its efficacy comparable to some conventional antidepressants. It is named for its traditional harvest on St. John's Day.
St. John's Wort (Hypericum perforatum) is the most extensively studied botanical antidepressant, with Level A evidence for mild to moderate depression. Standardized extracts (0.3% hypericin, 2-4% hyperforin) demonstrate efficacy comparable to SSRIs.
Hyperforin inhibits serotonin, norepinephrine, and dopamine reuptake non-competitively. Also modulates NMDA receptors. St. John's Wort is a potent CYP3A4 and P-glycoprotein inducer, explaining many drug interactions.