Sutherlandia Frutescens vs Shiitake

Side-by-side comparison of medicinal herbs

Herb

Sutherlandia Frutescens

Lessertia frutescens

Immune Support

Lentinula edodes

Immune Support

Sutherlandia Frutescens

❌ Not recommended in pregnancy

❌ Not recommended while nursing

Shiitake

✅ Generally safe in pregnancy

✅ Generally safe while nursing

Description

South African cancer bush used as traditional immune tonic. Contains L-canavanine and pinitol with adaptogenic properties.

Popular culinary and medicinal mushroom from East Asia. Contains lentinan with significant immune-modulating properties.

Active Compounds

L-canavanine, pinitol, GABA, flavonoids, saponins

lentinan, eritadenine, L-ergothioneine, beta-glucans

Traditional Uses

Treating wasting diseases, Boosting immunity, Treating cancer (folk use)

Boosting immunity, Treating fatigue, Supporting liver function

Modern Uses

Immune modulation, Adaptogenic effects, Blood sugar regulation

Immune enhancement, Cholesterol reduction, Anti-viral effects

Adult Dosage

2-3g dried leaf powder daily

3-8g dried mushroom daily or 1-3g extract

Contraindications

Pregnancy, Nursing, Antiretroviral medications without supervision

Autoimmune conditions, Mushroom allergies

Side Effects

Mild diarrhea initially, Dry mouth

Shiitake dermatitis from raw consumption, Digestive upset

Drug Interactions

0 known interactions

Reviewed by: HerbAlly Editorial Team, Medical herbalists and healthcare professionals

Sources: WHO Monographs · NCCIH · PubMed · Commission E