Allium Victorialis (Allium victorialis): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Allium victorialis work in the body?

Allium victorialis exerts its effects through several bioactive compounds. Allicin, released when plant tissues are crushed, provides antimicrobial and cardiovascular benefits by inhibiting bacterial growth and promoting circulation. Flavonoids like quercetin offer antioxidant protection and strengthen blood vessel walls. Adenosine contributes to cardiovascular protective effects by regulating heart rhythm and improving blood flow. These compounds work synergistically to support digestion, circulation, and immune function. Evidence level: C (preliminary research and traditional use).

Can I take Allium victorialis with blood thinners?

Allium victorialis should be used with caution alongside anticoagulant medications. The herb contains allicin and sulfur compounds with mild blood-thinning properties. Combining it with prescription anticoagulants like warfarin, heparin, or antiplatelet drugs such as aspirin and clopidogrel may increase bleeding risk. Patients on blood-thinning therapy should consult a healthcare provider before using this herb. Monitor for signs of excessive bleeding, including easy bruising or prolonged bleeding from minor cuts. Evidence level: C (theoretical interaction based on constituent properties).

What is the recommended dosage for Allium victorialis?

Traditional adult dosages for Allium victorialis range from 5-10 grams of fresh bulb or leaves daily. Dried material can be prepared as a tea infusion using similar quantities. Fresh preparations typically contain higher levels of allicin than dried forms. Start with lower doses to assess individual tolerance, as sulfur compounds may cause digestive discomfort in sensitive individuals. Therapeutic use should be guided by a qualified herbalist or healthcare provider. Evidence level: Traditional use.

Is Allium victorialis safe during pregnancy?

Allium victorialis is generally considered safe during pregnancy when consumed in normal culinary amounts. As a relative of garlic and onions, it has a long history of traditional food use without documented adverse effects in pregnant women. However, concentrated extracts or therapeutic doses warrant consultation with a healthcare provider. The herb's mild blood-thinning properties suggest caution during late pregnancy or immediately before delivery. No specific pregnancy safety studies exist for this herb. Evidence level: Traditional use.

What are the health benefits of Allium victorialis?

Allium victorialis, known as mountain allium or Alpine leek, has been used traditionally for cardiovascular, digestive, and protective purposes. It supports heart health by promoting healthy circulation and blood vessel function. The herb stimulates digestion and appetite while providing antimicrobial activity against various pathogens. In Alpine folk medicine, it served as a protective tonic for overall health maintenance. Modern research supports potential antioxidant and cardioprotective properties, though clinical evidence remains limited. Evidence level: C (traditional use with preliminary scientific support).

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 21 articles PubMed · modèle : gemma4:31b

Résumé

Allium victorialis is an edible perennial herb used in traditional medicine and as a vegetable, demonstrating antioxidant, hepatoprotective, and cardioprotective properties in experimental models [PMID:25337587, PMID:34690775, PMID:40551413].

Contexte

Allium victorialis (also known as Alpine leek or Gyoja-ninniku) is a wild edible perennial herb distributed in regions including Northern Japan, China's Changbai Mountains, and the Dadu River-Minjiang River areas [PMID:11237191, PMID:34553046, PMID:40970164]. It is considered an endangered species in some regions due to overexploitation and habitat changes [PMID:34553046].

Usages traditionnels

It is recorded in the Compendium of Materia Medica (Ming Dynasty) and used in Korean traditional medicine for hemostasis, analgesia, anti-inflammation, antioxidation, and hepatoprotective effects [PMID:34690775, PMID:25337587].

Composés actifs

The herb contains sulfur compounds such as allyl trisulfides, dithiins, ajoene, methyl allyl disulfide, diallyl disulfide, dimethyl disulfide, and methyl allyl trisulfide [PMID:11237191]. Other identified components include selenium, flavonoids, ascorbic acid, chlorophyllin [PMID:20369631], allivictosides A-H [PMID:23149227], gitogenin 3-O-lycotetroside [PMID:11235811], and alliumonoate (a cyclopentane derivative) [PMID:21995684].

Mécanisme d'action

The herb's water extract prevents cardiotoxicity via antioxidant properties [PMID:40551413]. In alcoholic liver disease models, it promotes FXR activity, inhibits SREBP1 and its target genes, regulates lipin 1/2, and increases PPARα and its target genes to reduce lipid deposition and inflammation [PMID:34690775]. Certain flavonoid glycosides inhibit nitric oxide production in microglia cells [PMID:23149227].

Preuves cliniques

Preuve DDoxorubicin-Induced Cardiotoxicity

Water extract (AVE) protected mouse cardiomyocytes from toxicity, normalized abnormal heart rate and cQT prolongation, and reduced serum creatine kinase and lactate dehydrogenase [PMID:40551413]

Preuve DAlcoholic Liver Disease

Extracts significantly reduced serum transaminase and liver triglycerides and attenuated histopathological changes in mice [PMID:34690775]

Preuve DCancer/Tumor Growth

Methanol extracts showed apoptosis-inducing capabilities in human colon cancer HT-29 cells and cytotoxic activity against oral tumor cell lines [PMID:25337587, PMID:11848491, PMID:11235811]

Preuve DNeuroinflammation

Specific flavonoid glycosides (allivictoside B and F) inhibited nitric oxide production in murine microglia BV-2 cells [PMID:23149227]

Synthèse des preuves

The current evidence is based entirely on in vitro studies and animal models (Level D); there are no human clinical trials or systematic reviews provided.

Sources PubMed

1.PMID: 40551413 (2025) — Water Extract of Allium Victorialis L. Prevents Doxorubicin-Induced Cardiotoxicity Through Its Antioxidant Property. · Journal of medicinal food
2.PMID: 34553046 (2021) — Transcriptome analysis and genetic diversity of Allium victorialis germplasms from the Changbai Mountains. · Mitochondrial DNA. Part B, Resources
3.PMID: 25337587 (2014) — Chemopreventive and Anticancer Activities of Allium victorialis var. platyphyllum Extracts. · Journal of cancer prevention
4.PMID: 34690775 (2021) — Allium victorialis L. Extracts Promote Activity of FXR to Ameliorate Alcoholic Liver Disease: Targeting Liver Lipid Deposition and Inflammation. · Frontiers in pharmacology
5.PMID: 11237191 (2000) — Thermochemical transformation of sulfur compounds in Japanese domestic Allium, Allium victorialis L.

Allium Victorialis

Sources et citations

Calculer une dose sûre de Allium Victorialis

Alpinia zerumbet

Allium stipitatum

Rakkyo

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Allium Victorialis

Sources et citations

Calculer une dose sûre de Allium Victorialis

Plantes associées

Alpinia zerumbet

Allium stipitatum

Rakkyo

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales