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AG
Not CommonVérifié
Anise Green
Pimpinella anisum
Troubles digestifs et coliques depuis l'Égypte ancienne
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 29 articles PubMed · modèle : gemma4:31b
Résumé
Pimpinella anisum (Anise) is a medicinal herb used for its antimicrobial, gastroprotective, and galactagogue properties [PMID:30000835, 37446993, 17373749].
Contexte
Anise (Pimpinella anisum L.) is an aromatic plant widely used in folk medicine, pharmacy, and the food industry [PMID:22926042, 38334183].
Usages traditionnels
It has been used in folk medicine as an antiulcer, anticancer, antibacterial agent, and muscle relaxant [PMID:32145331].
Composés actifs
The primary bioactive compound is trans-anethole [PMID:27427817, 37446993, 26619825]. Other constituents include chlorogenic acid, naringenin, gallic acid, ellagic acid, taxifolin, coffeic acid, syringic acid, eugenol, cis-anethole, methylchavicol, anisaldehyde, estragole, anisketone, linalool, coumarins, catechins, scopeletin, umbelliferone, estrols, beta-farnesene, limonene, and alpha-pinene [PMID:30000835, 37446993].
Mécanisme d'action
Anethole and polyphenols are noted to modulate intestinal motility and provide antimicrobial activity [PMID:39770978]. In rat models, Pimpinella anisum seeds attenuate colorectal cancer via antioxidant, anti-inflammatory, and anti-apoptotic pathways [PMID:38103135].
Preuves cliniques
Preuve ABreast milk volume
A meta-analysis indicated a small increase in milk volume on day 1 postpartum, with low certainty evidence for an increase on day 7 [PMID:30000835]. A randomized controlled trial also reported a statistically significant difference in milk volume between intervention and placebo groups across several days [PMID:36681821].
Preuve BGastrointestinal symptoms of COVID-19
Evaluated as an add-on therapy using 25g of powdered aniseed twice daily for 2 weeks in a randomized, placebo-controlled trial [PMID:38292939].
Preuve DGastric ulcers (Animal model)
Aqueous suspension significantly inhibited gastric mucosal damage induced by necrotizing agents and indomethacin in rats [PMID:17373749].
Preuve DDiabetic wound healing (Animal model)
A 10% methanolic extract significantly decreased wound size and improved fibroblast numbers in diabetic rats [PMID:31600102].
Sécurité et effets indésirables
Aniseed can cause clinical allergy, including occupational rhinoconjunctivitis and gastrointestinal symptoms [PMID:12027075]. In fish models, concentrations above 100 mg L-1 caused 10% mortality [PMID:38630160].
Grossesse et allaitement
Maternal ingestion reportedly imparts an odor to breastmilk, possibly due to anethole excretion [PMID:30000835]. In term-pregnant rats, extracts attenuated spontaneous and agonist-induced uterine contractions [PMID:32145331].
Interactions médicamenteuses
In mice, aniseed essential oil significantly decreased the peak plasma concentration of acetaminophen after oral application [PMID:26619825]. It also significantly increased the analgesic effect of codeine and enhanced motor impairment caused by midazolam [PMID:22926042].
Synthèse des preuves
Evidence ranges from high-level meta-analyses and RCTs regarding lactation to preclinical animal studies for gastroprotection and wound healing; human clinical data for other indications are limited.
Sources PubMed
1.PMID: 30000835 (2006) — Chemical Constituents, Antioxidant Potential, and Antimicrobial Efficacy of Pimpinella anisum Extracts against Multidrug-Resistant Bacteria. · Microorganisms
2.PMID: 38103135 (2024) — Anise (Pimpinella anisum L.) attenuates azoxymethane-induced colorectal cancer by antioxidant, anti-inflammatory, and anti-apoptotic pathways in rats. · Environmental science and pollution research international
3.PMID: 37446993 (2023) — Pimpinella anisum L. Essential Oil a Valuable Antibacterial and Antifungal Alternative. · Plants (Basel, Switzerland)
4.PMID: 39770978 (2024) — Herbal Extracts Mixed with Essential Oils: A Network Approach for Gastric and Intestinal Motility Disorders. · Nutrients
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
· Dermatitis : contact, atopic, occupational, drug
6.PMID: 26619825 (2016) — Pharmacokinetic Herb-Drug Interaction between Essential Oil of Aniseed (Pimpinella anisum L., Apiaceae) and Acetaminophen and Caffeine: A Potential Risk for Clinical Practice. · Phytotherapy research : PTR
7.PMID: 38292939 (2024) — Efficacy and safety of aniseed powder for treating gastrointestinal symptoms of COVID-19: a randomized, placebo-controlled trial. · Frontiers in pharmacology
8.PMID: 22926042 (2012) — The influence of essential oil of aniseed (Pimpinella anisum, L.) on drug effects on the central nervous system. · Fitoterapia
9.PMID: 31600102 (2019) — Wound healing activity of Pimpinella anisum methanolic extract in streptozotocin-induced diabetic rats. · Journal of wound care
10.PMID: 17373749 (2007) — Aqueous suspension of anise "Pimpinella anisum" protects rats against chemically induced gastric ulcers. · World journal of gastroenterology
11.PMID: 38630160 (2024) — Efficacy of fennel (Foeniculum vulgare) and anise (Pimpinella anisum) essential oils as anaesthesics in common carp (Cyprinus carpio L. 1758). · Fish physiology and biochemistry
12.PMID: 36681821 (2023) — The effect of Pimpinella Anisum herbal tea on human milk volume and weight gain in the preterm infant: a randomized controlled clinical trial. · BMC complementary medicine and therapies
13.PMID: 32145331 (2020) — Pimpinella anisum extract attenuates spontaneous and agonist-induced uterine contraction in term-pregnant rats. · Journal of ethnopharmacology
14.PMID: 12027075 (2002) — Occupational rhinoconjunctivitis and food allergy because of aniseed sensitization. · Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology