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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Calotropis gigantea
Mauvaise herbe pan-tropicale ; latex utilisé en Ayurveda pour les maladies de peau, les douleurs articulaires et comme purgatif ; contient des glycosides cardiotoniques.
Calotropis gigantea is a pan-tropical weed used in Ayurveda for skin diseases, joint pain, and as a purgative. Its primary active compounds include cardiac glycosides such as calotropin and calacin, which confer anti-inflammatory, analgesic, and topical antimicrobial properties. However, internal use is highly toxic due to cardiac glycoside content, limiting its modern application to topical formulations.
Cardiac glycosides (calotropin, calacin) inhibit Na+/K+-ATPase, increasing intracellular calcium and exerting positive inotropic effects, but also causing cardiotoxicity. Anti-inflammatory activity is mediated through inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis. Topical antimicrobial effects are attributed to disruption of bacterial cell membranes by calotropin and other compounds. Analgesic effects may involve opioid receptor modulation and peripheral anti-inflammatory actions.
Mauvaise herbe pan-tropicale ; latex utilisé en Ayurveda pour les maladies de peau, les douleurs articulaires et comme purgatif ; contient des glycosides cardiotoniques.
Calotropis gigantea is a pan-tropical weed used in Ayurveda for skin diseases, joint pain, and as a purgative. Its primary active compounds include cardiac glycosides such as calotropin and calacin, which confer anti-inflammatory, analgesic, and topical antimicrobial properties. However, internal use is highly toxic due to cardiac glycoside content, limiting its modern application to topical formulations.
Cardiac glycosides (calotropin, calacin) inhibit Na+/K+-ATPase, increasing intracellular calcium and exerting positive inotropic effects, but also causing cardiotoxicity. Anti-inflammatory activity is mediated through inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis. Topical antimicrobial effects are attributed to disruption of bacterial cell membranes by calotropin and other compounds. Analgesic effects may involve opioid receptor modulation and peripheral anti-inflammatory actions.