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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Polygonum multiflorum
Celebrated TCM anti-aging tonic used to nourish liver and kidney, replenish essence, treat hair graying, and as a general longevity tonic. Now associated with liver toxicity if unprepared.
Fo-Ti Root (Polygonum multiflorum) is a traditional Chinese medicinal herb renowned for its anti-aging properties, used to nourish the liver and kidneys, replenish essence, and treat premature hair graying. Its primary active compounds include stilbene glycosides (e.g., tetrahydroxystilbene glucoside), emodin, questin, and rhein, which contribute to its hepatoprotective, antioxidant, and adaptogenic effects. However, the raw, unprocessed form is associated with significant hepatotoxicity, and only the prepared (Zhi He Shou Wu) form is considered safe for therapeutic use.
The hepatoprotective effects of processed Fo-Ti are primarily attributed to stilbene glycosides, which activate the Nrf2/ARE pathway, upregulating antioxidant enzymes like superoxide dismutase and glutathione peroxidase, while inhibiting NF-κB-mediated inflammation. Emodin and other anthraquinones exert mild laxative and anti-aging effects through modulation of SIRT1 and telomerase activity, but also contribute to hepatotoxicity via mitochondrial dysfunction and oxidative stress in the raw form. Adaptogenic properties involve regulation of the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol levels and improving stress resilience. Additionally, the herb may influence melanogenesis through tyrosinase inhibition, supporting its traditional use for hair graying.
Celebrated TCM anti-aging tonic used to nourish liver and kidney, replenish essence, treat hair graying, and as a general longevity tonic. Now associated with liver toxicity if unprepared.
Fo-Ti Root (Polygonum multiflorum) is a traditional Chinese medicinal herb renowned for its anti-aging properties, used to nourish the liver and kidneys, replenish essence, and treat premature hair graying. Its primary active compounds include stilbene glycosides (e.g., tetrahydroxystilbene glucoside), emodin, questin, and rhein, which contribute to its hepatoprotective, antioxidant, and adaptogenic effects. However, the raw, unprocessed form is associated with significant hepatotoxicity, and only the prepared (Zhi He Shou Wu) form is considered safe for therapeutic use.
The hepatoprotective effects of processed Fo-Ti are primarily attributed to stilbene glycosides, which activate the Nrf2/ARE pathway, upregulating antioxidant enzymes like superoxide dismutase and glutathione peroxidase, while inhibiting NF-κB-mediated inflammation. Emodin and other anthraquinones exert mild laxative and anti-aging effects through modulation of SIRT1 and telomerase activity, but also contribute to hepatotoxicity via mitochondrial dysfunction and oxidative stress in the raw form. Adaptogenic properties involve regulation of the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol levels and improving stress resilience. Additionally, the herb may influence melanogenesis through tyrosinase inhibition, supporting its traditional use for hair graying.