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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Garcinia xanthochymus
An Asian tree with xanthone-rich bark and fruit used in folk medicine for antimicrobial and digestive conditions.
Garcinia xanthochymus is an Asian tree whose bark and fruit are rich in xanthones, gambogic acid, and morellic acid. It is traditionally used for digestive conditions, antimicrobial infections, and inflammation, while modern research focuses on its antimicrobial and anticancer potential, particularly through gambogic acid. Evidence is limited to pilot studies and traditional use (Level C).
Gambogic acid and xanthones exert antimicrobial effects by disrupting bacterial cell membranes and inhibiting biofilm formation. In cancer cells, gambogic acid induces apoptosis via mitochondrial pathway activation, caspase-3/9 cleavage, and inhibition of NF-κB signaling. Xanthones also inhibit cyclooxygenase-2 (COX-2) and lipoxygenase (LOX), contributing to anti-inflammatory activity. Additionally, these compounds may modulate P-glycoprotein efflux pumps, enhancing drug sensitivity in resistant cells.
An Asian tree with xanthone-rich bark and fruit used in folk medicine for antimicrobial and digestive conditions.
Garcinia xanthochymus is an Asian tree whose bark and fruit are rich in xanthones, gambogic acid, and morellic acid. It is traditionally used for digestive conditions, antimicrobial infections, and inflammation, while modern research focuses on its antimicrobial and anticancer potential, particularly through gambogic acid. Evidence is limited to pilot studies and traditional use (Level C).
Gambogic acid and xanthones exert antimicrobial effects by disrupting bacterial cell membranes and inhibiting biofilm formation. In cancer cells, gambogic acid induces apoptosis via mitochondrial pathway activation, caspase-3/9 cleavage, and inhibition of NF-κB signaling. Xanthones also inhibit cyclooxygenase-2 (COX-2) and lipoxygenase (LOX), contributing to anti-inflammatory activity. Additionally, these compounds may modulate P-glycoprotein efflux pumps, enhancing drug sensitivity in resistant cells.