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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Guarea guidonia
Neotropical Meliaceae tree; bark and leaves used in Caribbean and Latin American folk medicine for skin and infections.
Guarea guidonia is a Neotropical tree from the Meliaceae family, traditionally used in Caribbean and Latin American folk medicine for skin infections, fever, and digestive complaints. Its bark and leaves contain bioactive limonoids, flavonoids, tannins, and alkaloids, which contribute to antimicrobial, antipyretic, and digestive stimulant properties. Evidence is primarily traditional and preliminary (Level C), with limited clinical studies supporting its antimicrobial and anti-inflammatory effects.
The antimicrobial activity is attributed to limonoids (e.g., gedunin) that disrupt bacterial cell membranes and inhibit efflux pumps, while flavonoids and tannins provide antioxidant and astringent effects. Antipyretic and anti-inflammatory actions may involve inhibition of cyclooxygenase (COX) and nuclear factor-kappa B (NF-κB) pathways, reducing prostaglandin synthesis. The digestive stimulant and emetic effects are likely due to alkaloids and bitter principles that enhance gastric secretion and activate vagal reflexes. However, specific receptor-level mechanisms remain poorly characterized.
Neotropical Meliaceae tree; bark and leaves used in Caribbean and Latin American folk medicine for skin and infections.
Guarea guidonia is a Neotropical tree from the Meliaceae family, traditionally used in Caribbean and Latin American folk medicine for skin infections, fever, and digestive complaints. Its bark and leaves contain bioactive limonoids, flavonoids, tannins, and alkaloids, which contribute to antimicrobial, antipyretic, and digestive stimulant properties. Evidence is primarily traditional and preliminary (Level C), with limited clinical studies supporting its antimicrobial and anti-inflammatory effects.
The antimicrobial activity is attributed to limonoids (e.g., gedunin) that disrupt bacterial cell membranes and inhibit efflux pumps, while flavonoids and tannins provide antioxidant and astringent effects. Antipyretic and anti-inflammatory actions may involve inhibition of cyclooxygenase (COX) and nuclear factor-kappa B (NF-κB) pathways, reducing prostaglandin synthesis. The digestive stimulant and emetic effects are likely due to alkaloids and bitter principles that enhance gastric secretion and activate vagal reflexes. However, specific receptor-level mechanisms remain poorly characterized.