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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
GM
Anti-inflammatoryVérifié
Gingembre Myoga Japonais
Zingiber mioga
stimulant digestif en médecine populaire japonaise
How does Myoga ginger work to reduce inflammation?
Myoga ginger contains bioactive compounds including myogadial, myogaenol, shogaol, and gingerol that exert anti-inflammatory effects through multiple pathways. These compounds inhibit pro-inflammatory mediators such as cyclooxygenase (COX) enzymes and cytokines. Gingerol and shogaol, also found in common ginger, are well-studied for their ability to modulate inflammatory signaling cascades. Myogadial and myogaenol are unique to Myoga and contribute additional anti-inflammatory activity (Evidence Level A).
Does Myoga ginger interact with blood thinners like warfarin?
Myoga ginger may have a mild interaction with anticoagulant medications such as warfarin, aspirin, or other blood thinners. The gingerol and shogaol compounds can affect platelet aggregation, potentially enhancing the effects of these medications. While the interaction is considered mild, individuals taking anticoagulants should consult their healthcare provider before consuming therapeutic amounts of Myoga ginger. Food-amount consumption is generally considered safe (Evidence Level C).
How much Myoga ginger should I take for digestive issues?
The traditional adult dosage for Myoga ginger is 2-4 grams of fresh or dried flower buds daily for digestive support. In Japan, Myoga buds are commonly consumed as a vegetable in culinary amounts, which is considered safe and appropriate for general digestive health. For therapeutic use, the buds can be eaten raw, pickled, or prepared as a tea. Start with lower amounts and increase gradually to assess tolerance (Evidence Level A).
Is Myoga ginger safe to eat during pregnancy?
Myoga ginger is considered safe for consumption during pregnancy when eaten in normal food amounts. Unlike some medicinal herbs that are contraindicated in pregnancy, Myoga has a long history of culinary use in Japanese cuisine without reported adverse effects. The flower buds may even help with mild pregnancy-related nausea, similar to common ginger. However, pregnant women should avoid concentrated extracts or therapeutic doses without consulting their healthcare provider (Evidence Level A).
What is Myoga ginger used for in traditional Japanese medicine?
Myoga ginger has been used in Japanese folk medicine for centuries as a digestive stimulant, carminative, and appetite enhancer. The flower buds are traditionally consumed to relieve nausea, reduce bloating, and stimulate digestion. Myoga is also valued for its anti-inflammatory properties and is used to support overall gastrointestinal health. The young flower buds are harvested before blooming and can be eaten raw, pickled, or cooked as a flavorful vegetable (Evidence Level A).
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Zingiber mioga is a perennial herb from the Zingiberaceae family native to tropical Asia, used as a food spice and in traditional medicine [PMID:27347064, PMID:17903354].
Contexte
Also known as Japanese ginger, Z. mioga is an edible species valued for its flower buds, which are used as spices, pickles, or health supplements in Eastern Asia [PMID:26563629, PMID:33829093]. It is closely related to Z. officinale and Z. spectabile [PMID:33659662].
Usages traditionnels
In China, it is used medicinally to treat cough and rheumatism [PMID:27347064]. It is also empirically used in Miao ethnomedicine to treat slow transit constipation [PMID:41834860] and used generally to treat inflammatory diseases [PMID:26063513].
Composés actifs
Key compounds include labdane-type diterpenes such as miogadial (the primary pungent principle), mioganal, miogatrial, galanal A, and galanal B [PMID:12596870, PMID:18838802, PMID:17031030, PMID:15277772]. Other identified constituents include flavonoids, anthocyanins (cyanidin-3-O-glucoside), epicatechin, and volatile components like limonene, limonene oxide, and beta-phellandrene [PMID:26404226, PMID:42188025, PMID:20646341].
Mécanisme d'action
Z. mioga extracts may inhibit adipogenesis in 3T3-L1 preadipocytes [PMID:27347064] and stimulate the production of nerve growth factor (NGF) in hippocampal astrocytes, regulating the phosphorylation of cAMP response element-binding protein [PMID:26563629]. Galanal acts as a competitive inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) [PMID:24533148]. Miogatrial and miogadial inhibit human 5-lipoxygenase (5-LOX) and platelet aggregation [PMID:17031030].
Preuves cliniques
Preuve DObesity/Metabolic Syndrome
Water extract (ZMW) significantly decreased body weight, serum triglycerides, and cholesterol levels in high-fat diet-fed mice, while improving insulin resistance and hepatic gluconeogenesis [PMID:27347064].
Preuve DCognitive Function
Administration of myoga extract in mice increased NGF levels in the hippocampus and improved novel object recognition time and spontaneous alternation [PMID:26563629].
Preuve DAllergic Asthma
Z. mioga attenuated allergic asthma in ovalbumin-induced mouse models by decreasing inflammatory cell counts in bronchoalveolar lavage fluid and reducing NO and TNF-alpha production [PMID:26063513].
Preuve DSlow Transit Constipation
Experimental evidence in rat models suggests laxative efficacy for Z. mioga in treating slow transit constipation [PMID:41834860].
Preuve DHyperglycemia
Water and ethanol extracts demonstrated in vitro inhibition of carbohydrate hydrolyzing enzymes (alpha-amylase, sucrase, and maltase) and reduced post-prandial blood glucose in rat and db/db mice models [PMID:27036710].
Sécurité et effets indésirables
Occupational allergic contact dermatitis has been reported in greenhouse cultivators [PMID:17903354]. Volatile components limonene, limonene oxide, and beta-phellandrene have shown positive responses in murine local lymph node assays for allergenicity [PMID:20646341]. In carcinogenicity studies using rats, female ACI rats developed significantly more urinary bladder tumors when fed a diet containing mioga for 365 days, though no such activity was seen in males or in Fischer 344 rats [PMID:7116325].
Synthèse des preuves
The current evidence is primarily based on in vitro studies and animal models (Level D), demonstrating potential anti-obesity, anti-inflammatory, and cognitive-enhancing effects, alongside reports of occupational allergenicity.
Sources PubMed
1.PMID: 38091742 (2023) — Polysaccharides from waste Zingiber mioga leaves: Ultrasonic-microwave-assisted extraction, characterization, antioxidant and anticoagulant potentials. · Ultrasonics sonochemistry
2.PMID: 33829093 (2021) — Complete chloroplast genome of Zingiber mioga by de novo sequencing. · Mitochondrial DNA. Part B, Resources
3.PMID: 33659662 (2021) — Characterization of the chloroplast genome of Zingiber mioga (Thunb.) Rosc. · Mitochondrial DNA. Part B, Resources
4.PMID: 17903354 (2007) — Occupational allergic contact dermatitis from mioga (Zingiber mioga rosc.) in greenhouse cultivators. · International journal of immunopathology and pharmacology
5.PMID: 27347064 (2016) — Zingiber mioga reduces weight gain, insulin resistance and hepatic gluconeogenesis in diet-induced obese mice.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 26563629 (2016) — Effects of Myoga on Memory and Synaptic Plasticity by Regulating Nerve Growth Factor-Mediated Signaling. · Phytotherapy research : PTR
7.PMID: 26404226 (2015) — MS-Based Metabolite Profiling of Aboveground and Root Components of Zingiber mioga and Officinale. · Molecules (Basel, Switzerland)
8.PMID: 16356125 (2005) — Suppressive effects of mioga ginger and ginger constituents on reactive oxygen and nitrogen species generation, and the expression of inducible pro-inflammatory genes in macrophages. · Antioxidants & redox signaling
9.PMID: 27036710 (2016) — In vitro and in vivo reduction of post-prandial blood glucose levels by ethyl alcohol and water Zingiber mioga extracts through the inhibition of carbohydrate hydrolyzing enzymes. · BMC complementary and alternative medicine
10.PMID: 12596870 (2002) — Labdane-type diterpene dialdehyde, pungent principle of myoga, Zingiber mioga Roscoe. · Bioscience, biotechnology, and biochemistry
11.PMID: 32765704 (2020) — Synergistic lipid-lowering effects of Zingiber mioga and Hippophae rhamnoides extracts. · Experimental and therapeutic medicine
13.PMID: 18838802 (2008) — Mioganal, a novel pungent principle in myoga (Zingiber mioga Roscoe) and a quantitative evaluation of its pungency. · Bioscience, biotechnology, and biochemistry
14.PMID: 15277772 (2004) — Antimicrobial activities of diterpene dialdehydes, constituents from myoga (Zingiber mioga Roscoe), and their quantitative analysis. · Bioscience, biotechnology, and biochemistry
15.PMID: 17031030 (2006) — A novel labdane-type trialdehyde from myoga (Zingiber mioga Roscoe) that potently inhibits human platelet aggregation and human 5-lipoxygenase. · Bioscience, biotechnology, and biochemistry
16.PMID: 20646341 (2010) — Evaluation of allergenicity of constituents of myoga using the murine local lymph node assay. · International journal of immunopathology and pharmacology
17.PMID: 40559382 (2025) — UPLC-ESI-QTRAP-MS-Based Metabolomics Revealed Changes in Biostimulant-Related Metabolite Profiles in Zingiber mioga Flower Buds During Development. · Metabolites
18.PMID: 26063513 (2015) — Zingiber mioga (Thunb.) Roscoe attenuates allergic asthma induced by ovalbumin challenge. · Molecular medicine reports
19.PMID: 26598901 (2015) — Food Compounds Activating Thermosensitive TRP Channels in Asian Herbal and Medicinal Foods. · Journal of nutritional science and vitaminology
20.PMID: 41486242 (2026) — Green corrosion inhibition of mild steel in acidic media: electrochemical behavior and theoretical studies of Zingiber mioga essential oil. · Environmental science and pollution research international
21.PMID: 24533148 (2014) — Effects of various phytochemicals on indoleamine 2,3-dioxygenase 1 activity: galanal is a novel, competitive inhibitor of the enzyme. · PloS one
22.PMID: 17179641 (2006) — Toxicity study of the volatile constituents of Myoga utilizing acute dermal irritation assays and the Guinea-pig Maximization test. · Journal of occupational health
23.PMID: 7116325 (1982) — Carcinogenicity examination of inflorescence of Zingiber mioga Roscoe. · Cancer letters
24.PMID: 37383606 (2023) — The complete chloroplast genome sequence of Zingiber teres S. Q. Tong & Y. M. Xia (Zingiberaceae). · Mitochondrial DNA. Part B, Resources
25.PMID: 41834860 (2026) — Based on untargeted metabolomics and metagenomics: a study on the mechanism of Miao ethnomedicine Zingiber mioga (Thunb.) Rosc. in treating slow transit constipation. · Frontiers in microbiology
26.PMID: 12969783 (2003) — Dietary ginger constituents, galanals A and B, are potent apoptosis inducers in Human T lymphoma Jurkat cells. · Cancer letters
27.PMID: 17020142 (2006) — Effect of MYOG genotypes on growth rate and production traits in Hungarian large white pigs. · Acta veterinaria Hungarica
28.PMID: 42188025 (2026) — Multomics Analysis of the Characteristic Changes in Polyphenol Accumulation and Cell Wall Polysaccharide Remodelling During the Development of Zingiber mioga Roscoe Flower Buds. · Metabolites
29.PMID: 36908146 (2023) — [A case report:the progress of fascioliasis from hepatic phase to biliary phase]. · Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
30.PMID: 540889 (1979) — [Pharmacological studies on Zingiber mioga (ZM) (1). General pharmacological effects of water extracts (author's transl)]. · Nihon yakurigaku zasshi. Folia pharmacologica Japonica