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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Mandevilla velutina
Climbing vine of the Brazilian cerrado, used in Brazilian folk medicine for pain and inflammation.
Mandevilla velutina is a climbing vine native to the Brazilian cerrado, traditionally used for pain and inflammatory conditions. Modern research supports its analgesic, anti-inflammatory, and wound-healing properties, attributed to compounds such as velutinol, triterpenes, flavonoids, and phenolic acids. Evidence is limited to preclinical and pilot studies (Level C), indicating potential but requiring further clinical validation.
The antinociceptive and anti-inflammatory effects of Mandevilla velutina are mediated through inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis. Velutinol and triterpenes modulate NF-κB signaling, decreasing pro-inflammatory cytokines (e.g., TNF-α, IL-6). Flavonoids contribute antioxidant activity, scavenging free radicals and reducing oxidative stress in inflamed tissues. Additionally, the plant may activate opioid receptors peripherally, contributing to analgesic effects.
Climbing vine of the Brazilian cerrado, used in Brazilian folk medicine for pain and inflammation.
Mandevilla velutina is a climbing vine native to the Brazilian cerrado, traditionally used for pain and inflammatory conditions. Modern research supports its analgesic, anti-inflammatory, and wound-healing properties, attributed to compounds such as velutinol, triterpenes, flavonoids, and phenolic acids. Evidence is limited to preclinical and pilot studies (Level C), indicating potential but requiring further clinical validation.
The antinociceptive and anti-inflammatory effects of Mandevilla velutina are mediated through inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis. Velutinol and triterpenes modulate NF-κB signaling, decreasing pro-inflammatory cytokines (e.g., TNF-α, IL-6). Flavonoids contribute antioxidant activity, scavenging free radicals and reducing oxidative stress in inflamed tissues. Additionally, the plant may activate opioid receptors peripherally, contributing to analgesic effects.