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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Leonurus cardiaca is a perennial herb used traditionally for nervous heart conditions, digestive disorders, and gynecological afflictions [PMID:23042598, PMID:31119169].
Contexte
Leonurus cardiaca is a perennial plant indigenous to central Europe and Scandinavia, also found in temperate Russia, central Asia, and North America [PMID:23042598]. The herb consists of aerial parts gathered during the flowering period [PMID:23042598].
Usages traditionnels
Traditionally used internally for nervous heart conditions, digestive disorders, bronchial asthma, climacteric symptoms, and amenorrhoea, and externally for wounds [PMID:23042598]. It has also been used as a cardiotonic and for treating dysmenorrhea, menopausal anxiety, and postpartum depression [PMID:31119169].
Composés actifs
Identified compounds include flavonoids (such as hyperoside, catechin, and rutin), phenolic acids (chlorogenic, caffeic, and rosmarinic acids), ellagic acid, monoterpenes, diterpenes, triterpenes, nitrogen-containing compounds, phenylpropanoids, volatile oils, sterols, tannins, and polysaccharides [PMID:23042598, PMID:33503956, PMID:39472158, PMID:42279633]. Stachydrine is also found in L. cardiaca [PMID:23923634].
Preuves cliniques
Preuve APostpartum hemorrhage (PPH) prevention
Motherwort injection, alone or combined with oxytocin, is used to prevent PPH after vaginal delivery, cesarean section, and induced abortion [PMID:29882344, PMID:31354850, PMID:35935833, PMID:40527062].
Preuve APost-partum blood loss
Add-on therapy of motherwort injection to carboprost tromethamine significantly reduced post-partum blood loss at 2h and 24h [PMID:30288846].
Preuve DBlood hyperviscosity
Intravenous administration of motherwort (Leonurus Heterophyllus Sweet) showed improvement in hemorheology, decreasing blood viscosity and fibrinogen volume [PMID:2589238].
Sécurité et effets indésirables
In a case report of hepatitis, motherwort was part of a herbal remedy containing mistletoe; however, mistletoe was identified as the probable cause of the illness [PMID:6779941].
Grossesse et allaitement
Motherwort injection is used in clinical practice for the prevention of uterine hemorrhage during and after delivery and abortion [PMID:29882344, PMID:35935833, PMID:40527062].
Synthèse des preuves
Strong evidence (Meta-analyses/SRs) exists for the use of motherwort injections in preventing postpartum hemorrhage, primarily based on L. japonicus. Evidence for L. cardiaca specifically is largely based on traditional use and phytochemical reviews.
Sources PubMed
1.PMID: 23042598 (2013) — Leonurus cardiaca L. (motherwort): a review of its phytochemistry and pharmacology. · Phytotherapy research : PTR
2.PMID: 40527062 (2025) — Motherwort synergized with oxytocin for postpartum hemorrhage prevention: Integrated clinical efficacy and mechanism exploration. · Phytomedicine : international journal of phytotherapy and phytopharmacology
3.PMID: 33503956 (2021) — Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts. · Plants (Basel, Switzerland)
4.PMID: 35935833 (2022) — Motherwort Injection for Preventing Uterine Hemorrhage in Women With Induced Abortion: A Systematic Review and Meta-Analysis of Randomized Evidence. · Frontiers in pharmacology
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
— Motherwort injection for preventing postpartum hemorrhage in pregnant women with cesarean section: A systematic review and meta-analysis.
· Journal of evidence-based medicine
6.PMID: 31119169 (2019) — Leonurus cardiaca L. as a Source of Bioactive Compounds: An Update of the European Medicines Agency Assessment Report (2010). · BioMed research international
7.PMID: 42279633 (2026) — Water Infusions of Motherwort (Leonurus cardiaca) as a Source of Chlorogenic Acid and Antioxidant Properties. · Foods (Basel, Switzerland)
8.PMID: 39472158 (2024) — Stable Leonurus cardiaca L. polysaccharide-stabilized palladium nanoparticles for sensitive colorimetric detection of acetylcholine. · International journal of biological macromolecules
9.PMID: 30288846 (2019) — Efficacy and safety of motherwort injection add-on therapy to carboprost tromethamine for prevention of post-partum blood loss: A meta-analysis of randomized controlled trials. · The journal of obstetrics and gynaecology research
10.PMID: 31354850 (2019) — Motherwort Injection for Preventing Postpartum Hemorrhage in Women with Vaginal Delivery: A Systematic Review and Meta-Analysis of Randomized Evidence. · Evidence-based complementary and alternative medicine : eCAM
11.PMID: 6779941 (1981) — Mistletoe hepatitis. · British medical journal (Clinical research ed.)
12.PMID: 2589238 (1989) — Effect of motherwort on blood hyperviscosity. · The American journal of Chinese medicine
13.PMID: 23923634 (2013) — Stachydrine in Leonurus cardiaca, Leonurus japonicus, Leonotis leonurus: detection and quantification by instrumental HPTLC and 1H-qNMR analyses. · Die Pharmazie