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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Centella asiatica (Malay)
Malay traditional herb identical to Gotu Kola but used in distinct Malaysian Jamu preparations for cognitive support, wound healing, and leprosy treatment.
Pegaga (Centella asiatica), also known as Gotu Kola, is a traditional Malay herb used in Jamu preparations for cognitive support, wound healing, and venous insufficiency. Its primary active compounds include triterpenoid saponins such as asiaticoside and madecassoside, along with asiatic acid and madecassic acid. Modern research supports its use for memory enhancement, anxiolytic effects, and acceleration of wound healing, though evidence is limited (Level C).
Centella asiatica enhances cognitive function through modulation of the cholinergic system, increasing acetylcholine levels and promoting neurite outgrowth via activation of the ERK and PI3K/Akt pathways. Its triterpenoids, particularly asiatic acid, stimulate collagen synthesis and fibroblast proliferation, accelerating wound healing. Anxiolytic effects are mediated by GABAergic activity, possibly through interaction with GABA-A receptors. The herb also exhibits venotonic properties by improving venous tone and microcirculation, likely due to flavonoid-induced nitric oxide production.
Malay traditional herb identical to Gotu Kola but used in distinct Malaysian Jamu preparations for cognitive support, wound healing, and leprosy treatment.
Pegaga (Centella asiatica), also known as Gotu Kola, is a traditional Malay herb used in Jamu preparations for cognitive support, wound healing, and venous insufficiency. Its primary active compounds include triterpenoid saponins such as asiaticoside and madecassoside, along with asiatic acid and madecassic acid. Modern research supports its use for memory enhancement, anxiolytic effects, and acceleration of wound healing, though evidence is limited (Level C).
Centella asiatica enhances cognitive function through modulation of the cholinergic system, increasing acetylcholine levels and promoting neurite outgrowth via activation of the ERK and PI3K/Akt pathways. Its triterpenoids, particularly asiatic acid, stimulate collagen synthesis and fibroblast proliferation, accelerating wound healing. Anxiolytic effects are mediated by GABAergic activity, possibly through interaction with GABA-A receptors. The herb also exhibits venotonic properties by improving venous tone and microcirculation, likely due to flavonoid-induced nitric oxide production.