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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Podocarpus macrophyllus
A Japanese ornamental with bark and leaves used in folk medicine; berries edible but seed coat toxic.
Podocarpus macrophyllus, an evergreen tree native to East Asia, is used in traditional medicine as a tonic and anti-inflammatory agent. Its leaves and bark contain podocarpic acid, biflavones, and tannins, which are thought to contribute to its purported anti-inflammatory and antioxidant properties. However, clinical evidence is limited (Level C), and the seeds are toxic due to neurotoxic compounds, necessitating caution.
Podocarpic acid, a diterpene, may inhibit cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis. Biflavones such as amentoflavone exhibit antioxidant activity by scavenging free radicals and modulating NF-κB signaling, thereby attenuating inflammatory cytokine production. Tannins contribute astringent and anti-inflammatory effects through protein precipitation and inhibition of pro-inflammatory enzymes. These mechanisms collectively support the traditional anti-inflammatory use, though rigorous pharmacological studies are lacking.
A Japanese ornamental with bark and leaves used in folk medicine; berries edible but seed coat toxic.
Podocarpus macrophyllus, an evergreen tree native to East Asia, is used in traditional medicine as a tonic and anti-inflammatory agent. Its leaves and bark contain podocarpic acid, biflavones, and tannins, which are thought to contribute to its purported anti-inflammatory and antioxidant properties. However, clinical evidence is limited (Level C), and the seeds are toxic due to neurotoxic compounds, necessitating caution.
Podocarpic acid, a diterpene, may inhibit cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis. Biflavones such as amentoflavone exhibit antioxidant activity by scavenging free radicals and modulating NF-κB signaling, thereby attenuating inflammatory cytokine production. Tannins contribute astringent and anti-inflammatory effects through protein precipitation and inhibition of pro-inflammatory enzymes. These mechanisms collectively support the traditional anti-inflammatory use, though rigorous pharmacological studies are lacking.