PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Proanthocyanidin fraction from the bark significantly reduced ear swelling in DNFB-induced mice [PMID:25925974]
Organic extracts from floral cones potentiated anticancer effects via the intrinsic apoptosis pathway [PMID:33441588]
Fruit extracts and specific constituents (e.g., taxoquinone, sugiol) significantly reduced Aβ aggregation [PMID:36770688]
Leaf essential oil (2-5%) showed strong anti-listerial effects in milk samples, with synergism when combined with nisin [PMID:25149373]
Evidence summary
PubMed sources
- 1.PMID: 37381601 (2023) — The Metasequoia genome and evolutionary relationships among redwoods. · Plant communications
- 2.PMID: 15481245 (2004) — Flavonoids from Metasequoia glyptostroboides. · Acta poloniae pharmaceutica
- 3.PMID: 36770688 (2023) — Anti-Amyloidogenic Effects of Metasequoia glyptostroboides Fruits and Its Active Constituents. · Molecules (Basel, Switzerland)
- 4.PMID: 27065758 (2016) — Growing with dinosaurs: natural products from the Cretaceous relict Metasequoia glyptostroboides Hu & Cheng-a molecular reservoir from the ancient world with potential in modern medicine. · Phytochemistry reviews : proceedings of the Phytochemical Society of Europe
- 5.PMID: 37507893 (2023)