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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Zanthoxylum americanum
Spiny shrub of North American woodlands; bark and berries used by Indigenous peoples for toothache and circulatory conditions.
Prickly Ash (Zanthoxylum americanum) is a spiny North American shrub whose bark and berries have been traditionally used by Indigenous peoples for toothache and circulatory conditions. Modern applications include circulatory stimulation, analgesia, and anti-inflammatory effects, attributed to alkaloids such as chelerythrine and berberine, along with xanthoxylin and volatile oils. Its evidence level is C, indicating limited clinical data supporting these uses.
Chelerythrine inhibits cyclooxygenase and lipoxygenase pathways, reducing prostaglandin synthesis and inflammation. Berberine activates AMPK and modulates NF-κB, contributing to anti-inflammatory and antimicrobial effects. Xanthoxylin may act as a local analgesic by desensitizing sensory nerve endings. The circulatory stimulant effect is thought to involve vasodilation via nitric oxide release, while tannins and resins provide astringent and antimicrobial actions.
Spiny shrub of North American woodlands; bark and berries used by Indigenous peoples for toothache and circulatory conditions.
Prickly Ash (Zanthoxylum americanum) is a spiny North American shrub whose bark and berries have been traditionally used by Indigenous peoples for toothache and circulatory conditions. Modern applications include circulatory stimulation, analgesia, and anti-inflammatory effects, attributed to alkaloids such as chelerythrine and berberine, along with xanthoxylin and volatile oils. Its evidence level is C, indicating limited clinical data supporting these uses.
Chelerythrine inhibits cyclooxygenase and lipoxygenase pathways, reducing prostaglandin synthesis and inflammation. Berberine activates AMPK and modulates NF-κB, contributing to anti-inflammatory and antimicrobial effects. Xanthoxylin may act as a local analgesic by desensitizing sensory nerve endings. The circulatory stimulant effect is thought to involve vasodilation via nitric oxide release, while tannins and resins provide astringent and antimicrobial actions.