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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Prunus serotina
North American cherry used by Native Americans for cough, cold, and fever; bark syrup historically popular.
Prunus serotina, also known as black cherry, is a North American tree whose bark has been traditionally used by Native Americans for cough, cold, and fever. Modern evidence (Level C) supports its use as an antitussive, antispasmodic, and mild sedative, attributed to compounds such as prunasin, benzaldehyde, and scopoletin. However, its cyanogenic glycoside content poses a risk of cyanide toxicity with excessive doses.
The primary active compound, prunasin, is a cyanogenic glycoside that hydrolyzes to yield hydrocyanic acid (HCN) and benzaldehyde. HCN is thought to depress the cough reflex via central nervous system sedation, while benzaldehyde contributes to antispasmodic effects. Tannins provide astringent properties, and scopoletin may offer additional antispasmodic and mild sedative activity through modulation of smooth muscle calcium channels. The overall mechanism involves a combination of central and peripheral actions, though high doses lead to cyanide toxicity by inhibiting cytochrome c oxidase in the mitochondrial electron transport chain.
North American cherry used by Native Americans for cough, cold, and fever; bark syrup historically popular.
Prunus serotina, also known as black cherry, is a North American tree whose bark has been traditionally used by Native Americans for cough, cold, and fever. Modern evidence (Level C) supports its use as an antitussive, antispasmodic, and mild sedative, attributed to compounds such as prunasin, benzaldehyde, and scopoletin. However, its cyanogenic glycoside content poses a risk of cyanide toxicity with excessive doses.
The primary active compound, prunasin, is a cyanogenic glycoside that hydrolyzes to yield hydrocyanic acid (HCN) and benzaldehyde. HCN is thought to depress the cough reflex via central nervous system sedation, while benzaldehyde contributes to antispasmodic effects. Tannins provide astringent properties, and scopoletin may offer additional antispasmodic and mild sedative activity through modulation of smooth muscle calcium channels. The overall mechanism involves a combination of central and peripheral actions, though high doses lead to cyanide toxicity by inhibiting cytochrome c oxidase in the mitochondrial electron transport chain.