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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Rauvolfia vomitoria
West African Rauwolfia; bark and root used for hypertension, mental conditions, and fever in traditional medicine.
Rauvolfia vomitoria, a West African shrub, is traditionally used for hypertension, mental illness, and fever. Its bark and root contain reserpine and ajmaline, which have antihypertensive and sedative properties, though modern evidence is limited (Level C). The herb is primarily used under strict medical supervision due to significant side effects and contraindications.
Reserpine irreversibly inhibits the vesicular monoamine transporter (VMAT), depleting catecholamines (norepinephrine, dopamine, serotonin) in central and peripheral neurons, leading to reduced sympathetic outflow and hypotension. Ajmaline, a class Ia antiarrhythmic, blocks sodium channels and prolongs cardiac repolarization. Other alkaloids may contribute to sedative and antipsychotic effects via dopamine receptor antagonism and GABAergic modulation.
West African Rauwolfia; bark and root used for hypertension, mental conditions, and fever in traditional medicine.
Rauvolfia vomitoria, a West African shrub, is traditionally used for hypertension, mental illness, and fever. Its bark and root contain reserpine and ajmaline, which have antihypertensive and sedative properties, though modern evidence is limited (Level C). The herb is primarily used under strict medical supervision due to significant side effects and contraindications.
Reserpine irreversibly inhibits the vesicular monoamine transporter (VMAT), depleting catecholamines (norepinephrine, dopamine, serotonin) in central and peripheral neurons, leading to reduced sympathetic outflow and hypotension. Ajmaline, a class Ia antiarrhythmic, blocks sodium channels and prolongs cardiac repolarization. Other alkaloids may contribute to sedative and antipsychotic effects via dopamine receptor antagonism and GABAergic modulation.