Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Leaf extracts (15 µg/ml) significantly inhibited ADP-stimulated platelet aggregation by 38-55% and decreased surface membrane expression of activated GPIIbIIIa receptor by 21% in whole blood [PMID:26836594]
Aqueous and ethanolic extracts of leaves and stems showed antibacterial activity against S. aureus and Staphylococcus epidermidis, with ethanolic leaf extract (LEtOH) showing a MIC of 0.16 ± 0.40-1.56 ± 0.23 mg/mL [PMID:40725002]
Leaf extracts inhibited cell viability in a concentration-dependent manner; the ethyl acetate fraction at 250 µg/mL decreased viability below 66% [PMID:28101119]
Rubus caesius is a component of the Algan Hemostatic Agent (AHA), a multi-herbal extract used to reduce bleeding time in a rat tail hemorrhage model [PMID:33107963]
Synthèse des preuves
Sources PubMed
- 1.PMID: 36234716 (2022) — Polyphenolic Characterization, Antioxidant, Antihyaluronidase and Antimicrobial Activity of Young Leaves and Stem Extracts from Rubus caesius L. · Molecules (Basel, Switzerland)
- 2.PMID: 26836594 (2016) — The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils. · Platelets
- 3.PMID: 40725002 (2025) — Rubus caesius L. (European Dewberry) Extracts as a Novel Therapeutic Strategy Against MRSA Strains. · International journal of molecular sciences
- 4.PMID: 25034034 (2014) — CD39/NTPDase-1 expression and activity in human umbilical vein endothelial cells are differentially regulated by leaf extracts from Rubus caesius and Rubus idaeus. · Cellular & molecular biology letters
- 5.PMID: 41182101