Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Compound Kushen Injection (containing Smilax glabra Roxb.) significantly improved complete remission and partial response rates compared to patients without the injection [PMID:38579051]
Topical application of extract and use in herb pairs (with Cimicifugae Rhizoma) improved psoriatic lesions in mouse models [PMID:35963195, PMID:40876428]
Demonstrated uric acid lowering effects by regulating renal urate transporters (upregulating OAT1/ABCG2, downregulating URAT1) and remodeling intestinal microbiota in mice [PMID:40624868, PMID:37132060]
Alleviated AKI in mice by activating the Nrf2/HO-1 signaling pathway [PMID:40043544]
Engeletin and polysaccharides from S. glabra mitigated intestinal mucosal damage and restored barrier integrity in mice [PMID:40427406, PMID:37836386]
Synthèse des preuves
Sources PubMed
- 1.PMID: 40043544 (2025) — Smilax glabra roxb. alleviates cisplatin-induced acute kidney injury in mice by activating the Nrf2/HO-1 Signalling Pathway. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 35963195 (2022) — Combining network pharmacology, RNA-seq, and metabolomics strategies to reveal the mechanism of Cimicifugae Rhizoma - Smilax glabra Roxb herb pair for the treatment of psoriasis. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 3.PMID: 38820662 (2024) — Astilbin inhibited neutrophil extracellular traps in gouty arthritis through suppression of purinergic P2Y6 receptor. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 4.PMID: 41477354 (2025) — Butyrylated Smilax glabra starch relieves atopic dermatitis through gut-skin axis modulation via colon-targeted delivery. · Acta pharmaceutica Sinica. B
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