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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Smilax regelii
Mexican and Central American climbing vine with large roots, major commercial sarsaparilla source.
Smilax regelii, a climbing vine native to Mexico and Central America, is a primary commercial source of sarsaparilla. It is traditionally used for rheumatism and skin diseases, and modern research suggests anti-inflammatory, blood-purifying, and prebiotic gut-support properties. Key active compounds include steroidal saponins (sarsaponin, smilagenin), sitosterol, and flavonoids.
The anti-inflammatory effects are attributed to steroidal saponins (e.g., sarsaponin) that inhibit cyclooxygenase-2 (COX-2) and nuclear factor-kappa B (NF-κB) pathways, reducing pro-inflammatory cytokines. Sarsaponin and smilagenin may also modulate androgen receptor activity, contributing to historical use as a blood tonic. The prebiotic effect is thought to involve fermentation of saponins by gut microbiota, producing short-chain fatty acids that support intestinal barrier function. Flavonoids provide additional antioxidant activity via free radical scavenging.
Mexican and Central American climbing vine with large roots, major commercial sarsaparilla source.
Smilax regelii, a climbing vine native to Mexico and Central America, is a primary commercial source of sarsaparilla. It is traditionally used for rheumatism and skin diseases, and modern research suggests anti-inflammatory, blood-purifying, and prebiotic gut-support properties. Key active compounds include steroidal saponins (sarsaponin, smilagenin), sitosterol, and flavonoids.
The anti-inflammatory effects are attributed to steroidal saponins (e.g., sarsaponin) that inhibit cyclooxygenase-2 (COX-2) and nuclear factor-kappa B (NF-κB) pathways, reducing pro-inflammatory cytokines. Sarsaponin and smilagenin may also modulate androgen receptor activity, contributing to historical use as a blood tonic. The prebiotic effect is thought to involve fermentation of saponins by gut microbiota, producing short-chain fatty acids that support intestinal barrier function. Flavonoids provide additional antioxidant activity via free radical scavenging.